Evaluating Vasorin as a biomarker in septic shock
Prognostic Interest of Vasorin in Septic Shock
NA · Centre Hospitalier Universitaire, Amiens · NCT06072508
This study is testing if a protein called Vasorin can help doctors predict how severe kidney problems might be in adults with septic shock.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 50 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Centre Hospitalier Universitaire, Amiens (other) |
| Locations | 1 site (Amiens) |
| Trial ID | NCT06072508 on ClinicalTrials.gov |
What this trial studies
This study investigates the role of Vasorin, a protein linked to blood pressure regulation, as a potential early biomarker for predicting the severity of Acute Kidney Injury (AKI) in patients experiencing septic shock. By analyzing blood samples from patients in intensive care units, the researchers aim to understand how Vasorin levels correlate with AKI severity and mortality outcomes. The study focuses on hospitalized adults with septic shock requiring vasopressors, regardless of their AKI status.
Who should consider this trial
Good fit: Ideal candidates for this study are adults aged 18 and older who are hospitalized in intensive care units with septic shock requiring vasopressors.
Not a fit: Patients with chronic respiratory failure, those in palliative care, or pregnant women may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved early identification of patients at risk for severe AKI and better management strategies in septic shock.
How similar studies have performed: While the specific role of Vasorin in this context is novel, previous studies have explored biomarkers in septic shock, indicating potential for success in similar approaches.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age ≥18 years old. * Hospitalized in intensive care or medical resuscitation units. * With a septic shock state defined by 2 mmol/l lactate sepsis, requiring vasopressors to maintain mean blood pressure 65 mmHg (despite adequate vascular filling). * Whether or not they have developed AKI. * Patient/family information and collection of non opposition Exclusion Criteria: * Patients with chronic respiratory failure. * Pregnant women. * Patients in palliative care. * Information for the patient/someone close and collection of his opposition
Where this trial is running
Amiens
- CHU Amiens-Picardie — Amiens, France (RECRUITING)
Study contacts
- Study coordinator: Julien Maizel, Pr
- Email: Maizel.julien@chu-amiens.fr
- Phone: 0322087807
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Sepsis, Acute Kidney Injury, vasorin, angiotensin II