Evaluating Ultrasound Patterns for Fetal Brain Malformations
Official title: The Role of Ultrasonography in Pregnancy in the Study of Fetal Central Nervous System Malformations
Run by IRCCS Azienda Ospedaliero-Universitaria di Bologna · NCT06788808 · Data updated 2026-11-12
This study is trying to see if new ultrasound patterns can help doctors better identify brain problems in unborn babies by comparing images from healthy and affected fetuses.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 45 Years |
| Sex | Women only |
| Enrollment | 80 (estimated) |
| Sponsor | IRCCS Azienda Ospedaliero-Universitaria di Bologna Academic / other |
| Locations | 1 site (Bologna, Bologna) |
| Status | Recruiting |
| Started | October 11, 2021 |
| Main results expected | December 31, 2026 |
| Study ends | December 31, 2026 |
| Registry record updated | January 30, 2025 |
| Trial ID | NCT06788808 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include women over 18 years old with a single pregnancy and a fetus diagnosed with a central nervous system malformation.
✕Probably not a fit
Patients with twin pregnancies will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to assess the correlation between new ultrasound patterns and fetal central nervous system (CNS) malformations. It involves a retrospective analysis of ultrasound images from fetuses diagnosed with brain malformations and compares them with images from healthy fetuses. The study seeks to identify new ultrasound features that could improve the clarity of diagnosing fetal malformations. Information on maternal age, pregnancy history, and types of CNS malformations will also be collected to enhance understanding of these conditions.
Why it matters
Potential benefit: If successful, this study could lead to improved prenatal diagnosis of fetal brain malformations, allowing for better management and care.
How similar studies have gone: Other studies have explored ultrasound patterns in fetal malformations, but this specific approach to identifying new patterns is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Women older than 18 years with single pregnancy and fetus with ultrasound diagnosis of central nervous system malformation (group A) * Women with single pregnancy and normoconformed fetuses (group B). Exclusion Criteria: * Twin pregnancy
Where it's running
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IRCCS Azienda Ospedaliero-Universitaria di Bologna
Bologna, Bologna, Italy Recruiting
Study contacts
- Principal investigator: Gianluigi Pilu, MD — IRCCS Azienda Ospedaliero-Universitaria di Bologna
- Study coordinator: Gianluigi Pilu, MD
- Email: gianluigi.pilu@aosp.bo.it
- Phone: 0512143493
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.