Evaluating Ultrasound Patterns for Fetal Brain Malformations
The Role of Ultrasonography in Pregnancy in the Study of Fetal Central Nervous System Malformations
This study is trying to see if new ultrasound patterns can help doctors better identify brain problems in unborn babies by comparing images from healthy and affected fetuses.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 80 (estimated) |
| Ages | 18 Years to 45 Years |
| Sex | Female |
| Sponsor | IRCCS Azienda Ospedaliero-Universitaria di Bologna Academic / other |
| Locations | 1 site (Bologna, Bologna) |
| Trial ID | NCT06788808 on ClinicalTrials.gov |
What this trial studies
This observational study aims to assess the correlation between new ultrasound patterns and fetal central nervous system (CNS) malformations. It involves a retrospective analysis of ultrasound images from fetuses diagnosed with brain malformations and compares them with images from healthy fetuses. The study seeks to identify new ultrasound features that could improve the clarity of diagnosing fetal malformations. Information on maternal age, pregnancy history, and types of CNS malformations will also be collected to enhance understanding of these conditions.
Who should consider this trial
Good fit: Ideal candidates include women over 18 years old with a single pregnancy and a fetus diagnosed with a central nervous system malformation.
Not a fit: Patients with twin pregnancies will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved prenatal diagnosis of fetal brain malformations, allowing for better management and care.
How similar studies have performed: Other studies have explored ultrasound patterns in fetal malformations, but this specific approach to identifying new patterns is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Women older than 18 years with single pregnancy and fetus with ultrasound diagnosis of central nervous system malformation (group A) * Women with single pregnancy and normoconformed fetuses (group B). Exclusion Criteria: * Twin pregnancy
Where this trial is running
Bologna, Bologna
- IRCCS Azienda Ospedaliero-Universitaria di Bologna — Bologna, Bologna, Italy (Recruiting)
Study contacts
- Principal investigator: Gianluigi Pilu, MD — IRCCS Azienda Ospedaliero-Universitaria di Bologna
- Study coordinator: Gianluigi Pilu, MD
- Email: gianluigi.pilu@aosp.bo.it
- Phone: 0512143493
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.