Evaluating tumor characteristics and treatment response in colorectal cancer patients
Official title: Predict - a Translational Study to Predict Tumour Response to Neoadjuvant Treatment
Run by Sahlgrenska University Hospital · NCT04130971 · Data updated 2026-11-12
This study is testing how different tumor features and treatments affect adults with colorectal cancer by collecting samples from their bodies to learn more about the disease.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 800 (estimated) |
| Sponsor | Sahlgrenska University Hospital Academic / other |
| Locations | 1 site (Gothenburg) |
| Status | Recruiting |
| Started | February 1, 2019 |
| Main results expected | December 31, 2025 |
| Study ends | December 31, 2027 |
| Registry record updated | November 7, 2023 |
| Trial ID | NCT04130971 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adults diagnosed with colorectal cancer.
✕Probably not a fit
Patients with conditions other than colorectal cancer will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study involves adult patients diagnosed with colorectal cancer at Sahlgrenska University Hospital. Participants will provide tissue samples through biopsies taken during endoscopic procedures, follow-up exams, and surgeries. Blood, urine, and mouth swab samples will also be collected at various time points to assess tumor characteristics and treatment responses. The study aims to gather comprehensive biological data to better understand colorectal cancer progression and treatment efficacy.
Why it matters
Potential benefit: If successful, this study could lead to improved personalized treatment strategies for colorectal cancer patients.
How similar studies have gone: Similar observational studies have shown promise in understanding cancer biology and treatment responses, suggesting potential for success in this approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Colorectal cancer Exclusion Criteria: * Not colorectal cancer
Where it's running
-
Dept. of Surgery, Sahlgrenska University Hospital/Ostra
Gothenburg, Sweden Recruiting
Study contacts
- Study coordinator: Eva Angenete
- Email: eva.angenete@vgregion.se
- Phone: 0760514441
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Biomarkers in Colorectal Cancer: A Longitudinal Study Using Biobanks and Blood Samples
This study tests whether clinical and molecular biomarkers from tumor tissue and blood can predict treatment response, recurrence, and survival in adults with colorectal cancer undergoing surgery.
-
Prehabilitation with Resistance, Aerobic, or Both Before Colorectal Surgery
Four pre-surgery exercise options (resistance, aerobic, both, or none) will be tested to see which best reduces complications after colorectal cancer surgery.
-
ctDNA blood test to spot buried cancer after surgery or treatment in colorectal cancer
A blood test that looks for specific KRAS mutations in circulating tumor DNA to see if colorectal cancer has left residual disease or is likely to relapse.
-
Multimodal Survival Predictor for Colorectal Liver Metastases After Surgery
Researchers are testing a tool that combines MRI-derived tumor features with clinical data to predict survival after surgery for colorectal liver metastases.
-
Methylscape test in body fluids for multi-cancer detection in Colombia
A simple blood, urine, or saliva test called Methylscape is being tested to see if it can detect multiple cancers and identify where the signal is coming from, using people with cancer and healthy volunteers in Colombia.
-
AI-powered stool image analysis to see if it matches FIT results in colorectal cancer screening
We’re testing whether AI-derived features from stool images can align with FIT results in adults being screened or evaluated for colorectal neoplasia.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.