Evaluating Troponin T Levels in Aortic Stenosis Patients
High-Sensitivity Troponin T Plasma Levels in Patients With Aortic Stenosis
Medical University Innsbruck · NCT02448485
This study is testing if measuring troponin T levels can help doctors better understand the severity of aortic stenosis in patients, whether they have symptoms or not.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 10000 (estimated) |
| Sex | All |
| Sponsor | Medical University Innsbruck (other) |
| Drugs / interventions | radiation |
| Locations | 1 site (Innsbruck, Tyrol) |
| Trial ID | NCT02448485 on ClinicalTrials.gov |
What this trial studies
The Tyrolean Aortic Stenosis Study-2 (TASS-2) aims to assess the clinical significance of minimally elevated troponin T plasma levels in patients with both symptomatic and asymptomatic aortic stenosis. The study seeks to address the challenges in diagnosing advanced aortic stenosis, where traditional methods may underestimate the severity of the condition. By utilizing high-sensitivity troponin levels as a potential risk stratification tool, the study hopes to provide a more objective measure that could lead to timely interventions. This observational study will involve patients diagnosed with aortic stenosis through echocardiography or invasive methods.
Who should consider this trial
Good fit: Ideal candidates for this study are patients diagnosed with aortic stenosis, whether symptomatic or asymptomatic.
Not a fit: Patients with acute coronary syndrome or endocarditis may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could improve the early detection and management of aortic stenosis, potentially preventing irreversible heart damage.
How similar studies have performed: While the use of troponin levels in other cardiac conditions has shown promise, this specific application in aortic stenosis is relatively novel and untested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * aortic stenosis detected by echocardiography / invasively Exclusion Criteria: * acute coronary syndrome * endocarditis
Where this trial is running
Innsbruck, Tyrol
- Medical University Innsbruck — Innsbruck, Tyrol, Austria (RECRUITING)
Study contacts
- Principal investigator: Wolfgang Dichtl, MD, PhD — Medical University Innsbruck
- Study coordinator: Wolfgang Dichtl, MD, PhD
- Email: dichtl@me.com
- Phone: 004351250481388
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Aortic Stenosis, Heart Failure, Syncope, Angina Pectoris