Evaluating thrombosis related to central venous catheters using advanced CT imaging

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to assess the prevalence of subclinical thromboses associated with central venous catheters (CVCs) through the use of a novel photon-counting computed tomography (CT) scan. It consists of two sub-studies: one involving deceased patients with CVCs undergoing autopsy, and another involving living patients with CVCs referred for CT scans without contrast. The results from the photon-counting CT will be compared to findings from clinical autopsies to evaluate its diagnostic performance. The study seeks to enhance understanding of CVC-related thrombosis and improve imaging techniques.

Why it matters

Who can join: the full rules

Substudy 1

Inclusion Criteria:

* Diseased patients with an indwelling central venous catheter and a clinical indication for autopsy
* Informed and signed consent from next of kind

Exclusion Criteria:

* None

Substudy 2 Inclusion Criteria

* Living patients with an indwelling central venous catheter who are referred to a CT scan without iv contrast
* Informed and signed consent from the patient

Exclusion Criteria

\- GFR \<15 mL/min/1.73 m2

Where it's running

• Intensive and Perioperative Care. Skåne University Hospital. Lund
  Lund, Skåne County, Sweden Recruiting

Study contacts

• Principal investigator: Thomas Kander — Lund University
• Study coordinator: Thomas Kander, PhD
• Email: thomas.kander@med.lu.se
• Phone: +4646171163

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.