Clinical trial Recruiting at 2 sites Interventional

Evaluating the use of ProVent-14 score by ICU clinicians for predicting patient mortality

Official title: Prognostic Estimates Among ICU Clinicians Caring for Patients Requiring Prolonged Mechanical Ventilation

Run by Rush University Medical Center · NCT06452797 · Data updated 2026-11-12

This study tests if using the ProVent-14 score helps ICU doctors better predict the chances of survival for patients on mechanical ventilation for 14 days.

More Mechanical Ventilation trials

Quick facts

Study typeInterventional
SexAll
Enrollment238 (estimated)
SponsorRush University Medical Center
Academic / other
Locations3 sites (Chicago, Illinois and 2 other locations)
StatusRecruiting
StartedJune 18, 2024
Main results expectedJune 15, 2027
Study endsJune 15, 2027
Registry record updatedSeptember 28, 2026
Trial IDNCT06452797 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are ICU day-shift attending physicians, fellows, advanced practice providers, or nurses caring for patients requiring invasive mechanical ventilation for 14-16 days.

Probably not a fit

Patients with neuromuscular diseases or those transitioning to comfort-focused care may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates how ICU clinicians utilize the ProVent-14 score, which predicts one-year mortality risk for patients on mechanical ventilation for 14 days. By comparing predictions made by clinicians who have access to the ProVent-14 score against those who do not, the study aims to assess the score's impact on decision-making accuracy. The ProVent-14 score is based on clinical variables measured on the 14th day of mechanical ventilation and has been validated for its predictive capabilities. The goal is to enhance prognostic accuracy in critical care settings.

Why it matters

Potential benefit: If successful, this study could improve the accuracy of mortality predictions for patients on prolonged mechanical ventilation, leading to better-informed clinical decisions.

How similar studies have gone: While the ProVent-14 score has been validated, this specific approach to evaluating its use by clinicians is novel and has not been extensively tested in prior studies.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* ICU day-shift attending physician, fellow physician, advanced practice provider, or nurse
* Caring directly for a patient who requires invasive mechanical ventilation, 14-16 days after initial intubation, not actively transitioning to comfort-focused care and not with a neuromuscular disease (i.e. ALS) as a cause of respiratory failure.

Exclusion Criteria:

* None

Where it's running

  • Rush University Medical Center
    Chicago, Illinois, United States
    Recruiting
  • University of North Carolina
    Chapel Hill, North Carolina, United States
    Recruiting
  • Rush Oak Park Hospital
    Oak Park, Illinois, United States
    Active not recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.