Evaluating the use of ProVent-14 score by ICU clinicians for predicting patient mortality
Prognostic Estimates Among ICU Clinicians Caring for Patients Requiring Prolonged Mechanical Ventilation
This study tests if using the ProVent-14 score helps ICU doctors better predict the chances of survival for patients on mechanical ventilation for 14 days.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 238 (estimated) |
| Sex | All |
| Sponsor | Rush University Medical Center Academic / other |
| Locations | 3 sites (Chicago, Illinois and 2 other locations) |
| Trial ID | NCT06452797 on ClinicalTrials.gov |
What this trial studies
This study investigates how ICU clinicians utilize the ProVent-14 score, which predicts one-year mortality risk for patients on mechanical ventilation for 14 days. By comparing predictions made by clinicians who have access to the ProVent-14 score against those who do not, the study aims to assess the score's impact on decision-making accuracy. The ProVent-14 score is based on clinical variables measured on the 14th day of mechanical ventilation and has been validated for its predictive capabilities. The goal is to enhance prognostic accuracy in critical care settings.
Who should consider this trial
Good fit: Ideal candidates for this study are ICU day-shift attending physicians, fellows, advanced practice providers, or nurses caring for patients requiring invasive mechanical ventilation for 14-16 days.
Not a fit: Patients with neuromuscular diseases or those transitioning to comfort-focused care may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could improve the accuracy of mortality predictions for patients on prolonged mechanical ventilation, leading to better-informed clinical decisions.
How similar studies have performed: While the ProVent-14 score has been validated, this specific approach to evaluating its use by clinicians is novel and has not been extensively tested in prior studies.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * ICU day-shift attending physician, fellow physician, advanced practice provider, or nurse * Caring directly for a patient who requires invasive mechanical ventilation, 14-16 days after initial intubation, not actively transitioning to comfort-focused care and not with a neuromuscular disease (i.e. ALS) as a cause of respiratory failure. Exclusion Criteria: * None
Where this trial is running
Chicago, Illinois and 2 other locations
- Rush University Medical Center — Chicago, Illinois, United States (Recruiting)
- Rush Oak Park Hospital — Oak Park, Illinois, United States (Active_not_recruiting)
- University of North Carolina — Chapel Hill, North Carolina, United States (Recruiting)
Study contacts
- Study coordinator: Jared Greenberg, MD
- Email: jared_greenberg@rush.edu
- Phone: 312-942-6744
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.