Evaluating the safety of immunotherapy for insect venom allergy

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to assess the safety of immunotherapy for patients with Hymenoptera venom allergy. It will analyze adverse reactions to the immunotherapy as well as allergic reactions to spontaneous hymenoptera stings. The study will involve participants aged 14 and older who are sensitized to hymenoptera venom and will collect data prospectively across multiple centers in Spain. Additionally, the quality of life of participants will be evaluated using a questionnaire before and after treatment.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. The study population consisted of allergic participants indicated for treatment with immunotherapy with hymenoptera venom (Apis mellifera or Vespula spp.) according to standard clinical practice.
2. Age equal to or older than 14 years, without gender differences.
3. Not having received immunotherapy with hymenoptera venom in the previous 5 years.
4. That they agree to participate in the study and sign the informed consent form. In the case of minors, the parent or guardian of the participant must also sign the informed consent form.

Exclusion Criteria:

1. Pregnant or breastfeeding women.
2. Having received immunotherapy with hymenoptera venom during the 5 years prior to the start of the study.
3. Participants who do not agree to participate and/or do not sign the informed consent form.
4. Participants who do not comply with the medical indications or do not show cooperation with respect to the immunotherapy treatment.
5. Participants with oncological diseases under active treatment or with autoimmune diseases under immunosuppressive treatment.
6. Participants in whom the administration of immunotherapy is contraindicated.

Where it's running

• Hospital Virgen del Puerto Plasencia
  Plasencia, Cáceres, Spain Recruiting
• Hospital Público Da Mariña
  Burela de Cabo, Lugo, Spain Recruiting
• Hospital Comarcal de Monforte de Lemos
  Monforte de Lemos, Lugo, Spain Recruiting
• Hospital de A Coruña
  A Coruña, Spain Recruiting
• Hospital Vall d' Hebron
  Barcelona, Spain Recruiting
• Hospital Universitario Lucus Augusti
  Lugo, Spain Recruiting

Study contacts

• Principal investigator: Francisco Javier Carballada, MD — Hospital Universitario Lucus Augusti
• Study coordinator: Miguel Casanovas, MD
• Email: mcasanovas@inmunotek.com
• Phone: +3491208942

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Immunotherapy for treating insect venom allergies.

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• Long-term effects of jack jumper ant venom immunotherapy

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• Testing B-regulatory Cells as a Marker for Allergen Immunotherapy Response

  This study tests whether changes in blood B-regulatory cells can signal successful allergen immunotherapy in adults with pollen, dust mite, or insect venom allergies.

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• Evaluating a new method to identify vespid venom allergy risks

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• Understanding why some patients don't respond to bee venom allergy treatment

  This study looks at why some people with bee venom allergies don't get better with treatment and tries to find out if certain allergens make the treatment less effective.

  Recruiting at 3 sites Medical University of Graz · Graz and 2 other locations · NCT04259359

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.