Evaluating the role of genetics in kidney disease progression
The Genetic Contribution to Progression of Kidney Disease
This study is trying to see how genetics affects the worsening of kidney diseases like acute kidney injury and chronic kidney disease in people, especially those with high blood pressure.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 10000 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Ospedale San Raffaele Academic / other |
| Locations | 1 site (Milan) |
| Trial ID | NCT06416761 on ClinicalTrials.gov |
What this trial studies
This observational study investigates how genetic factors contribute to the development and progression of various nephropathies, including acute kidney injury (AKI), chronic kidney disease (CKD), and autosomal dominant polycystic kidney disease (ADPKD). It focuses on understanding the impact of genetic polymorphisms on disease severity and progression, particularly in patients with hypertension and other related conditions. The study aims to identify specific genetic markers that may influence kidney health and disease outcomes, providing insights into personalized treatment approaches.
Who should consider this trial
Good fit: Ideal candidates include individuals diagnosed with specific renal diseases such as AKI, CKD, or ADPKD.
Not a fit: Patients without any diagnosed renal disease or those not meeting the specific inclusion criteria may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved understanding and management of kidney diseases through personalized medicine based on genetic profiles.
How similar studies have performed: Other studies have shown promising results in understanding the genetic basis of kidney diseases, indicating that this approach is both relevant and potentially impactful.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: . presence of specific renal disease Exclusion Criteria: * to be evaluated in the different sub-protocols
Where this trial is running
Milan
- IRCCS Ospedale San Raffaele — Milan, Italy (Recruiting)
Study contacts
- Study coordinator: Chiara Livia Lanzani, prof
- Email: lanzani.chiara@hsr.it
- Phone: +393408163279
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.