Evaluating the role of FDG-PET/CT in managing infective endocarditis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This multicentric observational study aims to assess the impact of FDG-PET/CT imaging on the management of patients suspected of having native valve infective endocarditis (NVE). Participants will be recruited from six different healthcare centers, including two specialized cardiac centers and four tertiary care hospitals. The study will focus on patients classified as having possible infective endocarditis according to the modified Duke criteria and will evaluate how FDG-PET/CT influences clinical decision-making. The study will include adults who can provide informed consent and tolerate the PET/CT procedure.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* 18 years of age or older, capable to provide informed consent;
* Referred for a FDG-PET/CT study
* Classified as having Possible IE prior to FDG-PET/CT imaging;
* Patients must be able to tolerate the physical/logistical requirements of a PET/CT scan.

Exclusion Criteria:

* Subjects with prosthetic cardiac valve and/or CIED;
* Pregnant or breastfeeding female;
* Body mass index \> 45 kg/m2.

Where it's running

• Montreal Heart Institute
  Montreal, Quebec, Canada Recruiting
• Jewish General Hospital
  Montreal, Quebec, Canada Recruiting
• Centre Hospitalier de l'Universite de Montreal
  Montreal, Quebec, Canada Not yet recruiting
• McGill University Health Center
  Montreal, Quebec, Canada Not yet recruiting
• University Institute of Cardiology and Respirology of Quebec
  Québec, Quebec, Canada Not yet recruiting
• Centre Hospitalier de l'Universite de Sherbrooke
  Sherbrooke, Quebec, Canada Not yet recruiting

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Barts Endocarditis Registry

  This registry collects health, imaging, microbiology, treatment, and outcome information from adults with infective endocarditis seen at Barts Heart Centre to learn which approaches work best.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.