Evaluating the link between thyroid dysfunction and fatty liver disease
Thyroid Dysfunction and Its Association With Metabolic Dysfunction-Associated Fatty Liver Disease
This study looks at how common thyroid problems are in adults with fatty liver disease to see if there's a connection between thyroid hormones and liver health.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 150 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Tanta University Academic / other |
| Locations | 1 site (Tanta, El-Gharbia) |
| Trial ID | NCT06739330 on ClinicalTrials.gov |
What this trial studies
This observational study aims to assess how prevalent thyroid dysfunction is among patients with metabolic dysfunction-associated fatty liver disease (MAFLD). It explores the relationship between thyroid hormone levels and liver health, given that thyroid hormones play a crucial role in metabolic processes. The study will involve adult participants diagnosed with MAFLD, utilizing tools like Fibroscan to evaluate liver condition. By understanding this association, the research seeks to shed light on potential risk factors for liver disease progression.
Who should consider this trial
Good fit: Ideal candidates for this study are adults aged 18 and older diagnosed with metabolic dysfunction-associated fatty liver disease.
Not a fit: Patients with a history of thyroid disease or treatment, alcoholic liver disease, viral hepatitis, or who are pregnant may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved screening and management strategies for patients with fatty liver disease by addressing thyroid health.
How similar studies have performed: While the association between thyroid dysfunction and liver disease has been suggested, this specific observational approach is relatively novel and not extensively tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age ≥ 18 years. * Both sexes. * Patients with metabolic dysfunction-associated fatty liver disease (MAFLD). Exclusion Criteria: * History of thyroid disease or treatment (e.g., thyroid nodules, thyroid cancer, hypothyroidism, and hyperthyroidism). * Patients with alcoholic liver disease take more than 40g of alcohol (or four units) per day. * Viral hepatitis. * Pregnant women.
Where this trial is running
Tanta, El-Gharbia
- Tanta University — Tanta, El-Gharbia, Egypt (Recruiting)
Study contacts
- Study coordinator: Shimaa A Meshaal, MD
- Email: shaimaa.meshaal2013@med.tanta.edu.eg
- Phone: 00966559806580
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.