Clinical trial Recruiting at 1 site Observational Ages 18 and up

Evaluating the link between thyroid dysfunction and fatty liver disease

Official title: Thyroid Dysfunction and Its Association With Metabolic Dysfunction-Associated Fatty Liver Disease

Run by Tanta University · NCT06739330 · Data updated 2026-11-12

This study looks at how common thyroid problems are in adults with fatty liver disease to see if there's a connection between thyroid hormones and liver health.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment150 (estimated)
SponsorTanta University
Academic / other
Locations1 site (Tanta, El-Gharbia)
StatusRecruiting
StartedDecember 19, 2024
Main results expectedMay 1, 2025
Study endsMay 1, 2025
Registry record updatedDecember 20, 2024
Trial IDNCT06739330 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are adults aged 18 and older diagnosed with metabolic dysfunction-associated fatty liver disease.

Probably not a fit

Patients with a history of thyroid disease or treatment, alcoholic liver disease, viral hepatitis, or who are pregnant may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to assess how prevalent thyroid dysfunction is among patients with metabolic dysfunction-associated fatty liver disease (MAFLD). It explores the relationship between thyroid hormone levels and liver health, given that thyroid hormones play a crucial role in metabolic processes. The study will involve adult participants diagnosed with MAFLD, utilizing tools like Fibroscan to evaluate liver condition. By understanding this association, the research seeks to shed light on potential risk factors for liver disease progression.

Why it matters

Potential benefit: If successful, this study could lead to improved screening and management strategies for patients with fatty liver disease by addressing thyroid health.

How similar studies have gone: While the association between thyroid dysfunction and liver disease has been suggested, this specific observational approach is relatively novel and not extensively tested.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age ≥ 18 years.
* Both sexes.
* Patients with metabolic dysfunction-associated fatty liver disease (MAFLD).

Exclusion Criteria:

* History of thyroid disease or treatment (e.g., thyroid nodules, thyroid cancer, hypothyroidism, and hyperthyroidism).
* Patients with alcoholic liver disease take more than 40g of alcohol (or four units) per day.
* Viral hepatitis.
* Pregnant women.

Where it's running

  • Tanta University
    Tanta, El-Gharbia, Egypt
    Recruiting

Study contacts

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.