Evaluating the impact of sarcopenia on lung cancer surgery outcomes in older patients
Association of Preoperative Sarcopenia on Postoperative Outcomes After Lung Cancer Surgery: Prospective Observational Study
This study looks at how having less muscle mass affects the surgery results for older patients with lung cancer.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 400 (estimated) |
| Ages | 70 Years and up |
| Sex | All |
| Sponsor | Seoul National University Hospital Academic / other |
| Locations | 1 site (Seoul) |
| Trial ID | NCT05346185 on ClinicalTrials.gov |
What this trial studies
This observational study aims to assess the role of sarcopenia as a clinical biomarker for risk stratification in elderly patients undergoing lung cancer surgery. It focuses on understanding how the presence of sarcopenia, characterized by decreased skeletal muscle mass and function, affects short-term and long-term surgical outcomes. The study will involve patients who are planning curative surgery for confirmed lung cancer or suspected pulmonary nodules. By analyzing the relationship between sarcopenia and surgical outcomes, the investigators hope to provide insights that could improve patient management and care.
Who should consider this trial
Good fit: Ideal candidates for this study are elderly patients planning to undergo curative surgery for lung cancer or suspected lung cancer.
Not a fit: Patients with a history of lung cancer treatment within the past five years or those requiring simultaneous surgery for other conditions may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance the ability to predict surgical risks and improve outcomes for elderly lung cancer patients with sarcopenia.
How similar studies have performed: Previous studies have indicated a significant association between sarcopenia and poor surgical outcomes in cancer patients, suggesting that this approach is supported by existing evidence.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients planning to perform curative surgery for confirmed lung cancer and pulmonary nodules suspected for lung cancer * Patients or legal representatives who could understand and write written consent prior to the initiation of the clinical trial and are able to comply with the requirements for the clinical trial Exclusion Criteria: * Patients with treatment history for lung cancer or other solid cancer within 5 years (except patients with adenocarcinoma in situ for lung cancer) * Patients who need simultaneous surgery with lung caner surgery for other accompanying diseases * Patients who are not eligible to participate in the study judged by the researcher
Where this trial is running
Seoul
- Seoul National University Hospital — Seoul, Korea, Republic of (Recruiting)
Study contacts
- Principal investigator: In Kyu Park, MD, PhD — Seoul National University Hospital, Department of Thoracic and Cardiovascular Surgery
- Study coordinator: Kwon Joong Na, MD
- Email: kjna85@gmail.com
- Phone: 82-10-3329-9392
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.