Evaluating the impact of fact boxes on vaccination decisions for COVID-19 and influenza

Do Evidence-based Fact Boxes Improve Informed Decision-making About COVID-19 and Influenza Vaccination in More and Less Disadvantaged Groups Equally? - Study Protocol for a Multi-center Cluster RCT in Health and Social Care in Germany

Not applicable Interventional Harding Center for Risk Literacy · NCT06076421

This study is testing if using easy-to-understand fact boxes can help people from different backgrounds in Germany make better decisions about getting COVID-19 and flu vaccines.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment800 (estimated)
Ages18 Years and up
SexAll
SponsorHarding Center for Risk Literacy Academic / other
Locations1 site (Potsdam, Brandenburg)
Trial IDNCT06076421 on ClinicalTrials.gov

What this trial studies

This study evaluates the effectiveness of evidence-based fact boxes designed to aid decision-making regarding COVID-19 and influenza vaccinations among individuals from diverse social backgrounds in Germany. It aims to determine whether these fact boxes can improve informed decision-making and promote equity in healthcare by addressing the needs of various educational and socioeconomic groups. The study employs a multi-center, cluster-randomized, cross-sectional design to compare the outcomes of participants using fact boxes against those receiving standard health education. The focus is on enhancing shared decision-making in vaccination contexts.

Who should consider this trial

Good fit: Ideal candidates include adults residing in Germany who speak Arabic, German, Russian, or Turkish and are currently facing a vaccination decision for themselves or a family member.

Not a fit: Patients who do not speak the eligible languages or who are not currently making a vaccination decision may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to more equitable health outcomes by improving vaccination decision-making across diverse populations.

How similar studies have performed: While the use of fact boxes in health communication has shown promise, this specific approach focusing on diverse social groups is relatively novel and has not been extensively tested.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Adults of legal age with current residence in Germany and who speak Arabic, German, Russian, Turkish
* People who are currently facing a decision about COVID-19 or influenza vaccination for themselves or a family member (e.g. caring relatives)
* Informed online consent

Exclusion Criteria:

* Language other than Arabic, German, Russian, Turkish
* People without a current vaccination decision
* No informed consent

Where this trial is running

Potsdam, Brandenburg

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions COVID-19Influenzahealth inequityinformed decision makingfact boxevidence-based health informationrisk communication
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.