Evaluating the impact of a single dose of antibiotics on dental implant success
The Effect of Pre-operative Single Dose Antibiotic Prophylaxis on the Post-operative Implant Success
This study tests if giving a single dose of antibiotics before getting a dental implant helps prevent complications and improves the success of the implant for people with tooth loss.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 50 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Biruni University Academic / other |
| Locations | 1 site (Istanbul) |
| Trial ID | NCT04856319 on ClinicalTrials.gov |
What this trial studies
This study investigates the effects of a pre-operative single dose of antibiotic prophylaxis on post-operative complications and the success of dental implants in individuals with tooth loss. It involves 50 participants who will receive either 2 g of amoxicillin and clavulanic acid or a placebo before undergoing dental implant placement. The study aims to provide clarity on the necessity of antibiotic use in dental implant procedures by comparing outcomes between the two groups. Additionally, it will consider other factors that may influence implant success, such as patient demographics and surgical variables.
Who should consider this trial
Good fit: Ideal candidates for this study are individuals experiencing tooth loss who do not have systemic diseases or are pregnant/lactating.
Not a fit: Patients with systemic diseases or those who are pregnant or lactating may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could establish guidelines for antibiotic use in dental implant procedures, potentially improving patient outcomes.
How similar studies have performed: While there is ongoing debate regarding antibiotic prophylaxis in dental implants, this study aims to fill gaps in existing literature, making it a novel approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Tooth loss Exclusion Criteria: * Systemic disease * Lactation/pregnancy
Where this trial is running
Istanbul
- Biruni University — Istanbul, Turkey (Recruiting)
Study contacts
- Principal investigator: Mustafa Yılmaz, PhD — Biruni University, assistant professor
- Study coordinator: Mustafa Yılmaz, PhD
- Email: myilmaz@biruni.edu.tr
- Phone: +905337129952
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.