Evaluating the ICCAN program's impact on cancer treatment and quality of life

A Randomized Controlled Trial of the Impact of ICCAN on Cancer Treatment Completion and Quality of Life

Observational Memorial Sloan Kettering Cancer Center · NCT01742143

This study is testing whether the ICCAN program can help cancer patients complete their treatment and improve their quality of life compared to regular hospital services.

Quick facts

Study typeObservational
Enrollment347 (estimated)
Ages21 Years to 80 Years
SexAll
SponsorMemorial Sloan Kettering Cancer Center Academic / other
Drugs / interventionschemotherapy, immunotherapy, radiation
Locations11 sites (Basking Ridge, New Jersey and 10 other locations)
Trial IDNCT01742143 on ClinicalTrials.gov

What this trial studies

This observational study aims to assess the effectiveness of the Integrated Cancer Care Access Network (ICCAN) program in improving treatment completion and quality of life for cancer patients. It compares the ICCAN program to standard hospital services available in New York City, such as social work and patient navigation. Participants include cancer patients currently undergoing or scheduled to begin chemotherapy or radiation therapy. The study will track outcomes over a one-year period to determine the program's impact.

Who should consider this trial

Good fit: Ideal candidates are cancer patients aged 21-80 who are currently receiving or scheduled to begin chemotherapy or radiation therapy.

Not a fit: Patients who are not currently undergoing chemotherapy or radiation therapy, or those who are only scheduled for surgery, may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance cancer treatment completion rates and improve the quality of life for patients undergoing therapy.

How similar studies have performed: Other studies have shown positive outcomes with integrated care approaches in cancer treatment, suggesting potential success for this program.

Eligibility criteria

Show full inclusion / exclusion criteria
Participant Inclusion Criteria:

Patient is eligible if he/she is

* fluent in English, Spanish, or Mandarin
* between the ages of 21-80 years old
* cancer patients currently receiving chemotherapy (started within the past month) and/or radiation therapy (started within the past week), or
* scheduled to begin chemotherapy and/or radiation therapy within the next 2 months (excluding surgery only patients)
* planning on remaining in the area for at least 1 year

Clinician is eligible if he/she:

* Has an MD or DO degree
* Is the treating physician providing care to a patient enrolled to the study

ICCAN-IO Phase 1: Refinement, participant is eligible if he/she per EMR or self-report:

* Is 18 - 85 years of age
* Has unresectable locally advanced, locally recurrent unresectable, metastatic, or high risk/early stage TNBC or stage I-IV lung cancer
* Eligible for FDA approved immunotherapy in the NYC metropolitan area (per self-report or per MSK patient EMR records).
* Is treated in the NY metropolitan area
* Self-identifies as Black or Hispanic, and/or is low-SES (low SES will be defined as household income \< 200% of federal poverty level)
* Has English or Spanish proficiency
* Agrees to be audio-recorded

ICCAN-IO Phase 2: Pilot RCT, participant is eligible if he/she per EMR or self-report:

* Is 18 - 85 years of age
* Has stage II-III TNBC
* Treated at MSK Manhattan or OneMSK regional sites
* Self identifies as Black or Hispanic, and/or is low SES (low SES will be defined as household income \< 200% of federal poverty level)
* Has English or Spanish proficiency
* Agrees to be audio-recorded

ICCAN-IO process evaluation study team participants only:

* Staff member who serves as an Access Facilitator
* Agrees to be audio-recorded

Participant Exclusion Criteria:

Patient is ineligible is he/she is:

* Presence of untreated psychiatric disturbance (i.e. acute psychiatric symptoms which require individual treatment) and/or cognitive impairment disorder (e.g., delirium or dementia) verified by medical record sufficient to preclude completion of the assessment measures, interview or informed consent

ICCAN-IO Phase 1: Refinement, participant is ineligible if he/she per EMR or self-report:

* Presence of untreated psychiatric disturbance (e.g., acute psychiatric symptoms which require individual treatment) and/or cognitive impairment disorder (e.g., delirium or dementia) sufficient to preclude completion of the assessment measures, interview or informed consent
* Participants or family members who are participating in MSK IHCD studies related to social determinants of health

ICCAN-IO Phase 2: Pilot RCT, participant is ineligible if he/she per EMR or self-report:

* Presence of untreated psychiatric disturbance (e.g, acute psychiatric symptoms which require individual treatment) and/or cognitive impairment disorder (e.g., delirium or dementia) sufficient to preclude completion of the assessment measures, interview or informed consent
* Participants or family members who are participating in MSK IHCD studies related to social determinants of health

Where this trial is running

Basking Ridge, New Jersey and 10 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Cancer PatientsQuality of lifecancer12-223
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.