Evaluating the ICCAN program's impact on cancer treatment and quality of life
Official title: A Randomized Controlled Trial of the Impact of ICCAN on Cancer Treatment Completion and Quality of Life
Run by Memorial Sloan Kettering Cancer Center · NCT01742143 · Data updated 2026-11-12
This study is testing whether the ICCAN program can help cancer patients complete their treatment and improve their quality of life compared to regular hospital services.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 21 Years to 80 Years |
| Sex | All |
| Enrollment | 347 (estimated) |
| Sponsor | Memorial Sloan Kettering Cancer Center Academic / other |
| Drugs / interventions | chemotherapy, immunotherapy, radiation |
| Locations | 11 sites (Basking Ridge, New Jersey and 10 other locations) |
| Status | Recruiting |
| Started | November 2012 |
| Main results expected | November 2027 |
| Study ends | November 2027 |
| Registry record updated | September 21, 2026 |
| Trial ID | NCT01742143 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are cancer patients aged 21-80 who are currently receiving or scheduled to begin chemotherapy or radiation therapy.
✕Probably not a fit
Patients who are not currently undergoing chemotherapy or radiation therapy, or those who are only scheduled for surgery, may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to assess the effectiveness of the Integrated Cancer Care Access Network (ICCAN) program in improving treatment completion and quality of life for cancer patients. It compares the ICCAN program to standard hospital services available in New York City, such as social work and patient navigation. Participants include cancer patients currently undergoing or scheduled to begin chemotherapy or radiation therapy. The study will track outcomes over a one-year period to determine the program's impact.
Why it matters
Potential benefit: If successful, this study could enhance cancer treatment completion rates and improve the quality of life for patients undergoing therapy.
How similar studies have gone: Other studies have shown positive outcomes with integrated care approaches in cancer treatment, suggesting potential success for this program.
Who can join: the full rules
Show full inclusion / exclusion criteria
Participant Inclusion Criteria: Patient is eligible if he/she is * fluent in English, Spanish, or Mandarin * between the ages of 21-80 years old * cancer patients currently receiving chemotherapy (started within the past month) and/or radiation therapy (started within the past week), or * scheduled to begin chemotherapy and/or radiation therapy within the next 2 months (excluding surgery only patients) * planning on remaining in the area for at least 1 year Clinician is eligible if he/she: * Has an MD or DO degree * Is the treating physician providing care to a patient enrolled to the study ICCAN-IO Phase 1: Refinement, participant is eligible if he/she per EMR or self-report: * Is 18 - 85 years of age * Has unresectable locally advanced, locally recurrent unresectable, metastatic, or high risk/early stage TNBC or stage I-IV lung cancer * Eligible for FDA approved immunotherapy in the NYC metropolitan area (per self-report or per MSK patient EMR records). * Is treated in the NY metropolitan area * Self-identifies as Black or Hispanic, and/or is low-SES (low SES will be defined as household income \< 200% of federal poverty level) * Has English or Spanish proficiency * Agrees to be audio-recorded ICCAN-IO Phase 2: Pilot RCT, participant is eligible if he/she per EMR or self-report: * Is 18 - 85 years of age * Has stage II-III TNBC * Treated at MSK Manhattan or OneMSK regional sites * Self identifies as Black or Hispanic, and/or is low SES (low SES will be defined as household income \< 200% of federal poverty level) * Has English or Spanish proficiency * Agrees to be audio-recorded ICCAN-IO process evaluation study team participants only: * Staff member who serves as an Access Facilitator * Agrees to be audio-recorded CCAN-GBM * Over the age of 18 (per EMR) * Diagnosed with Glioblastoma (per EMR) * Has not yet started radiation and concurrent temozolomide treatment (per EMR) * Has a primary neuro-oncologist at MSK (per EMR) * Will be undergoing radiation at MSK (per EMR) * Treatment plan consists of a 6-week or 3-week (hypofractionated) course of radiation and chemotherapy (per EMR) * Participant or caregiver is fluent in English or Spanish * Planning on remaining in the tri-state area during the 6 weeks or 3 weeks of radiation and chemotherapy (per self-report) * Screens positive on SDOH screening tool, referred by the clinical team through traditional screening tools for SDOH assistance (per EMR or self-report), demonstrates financial need per MSK guidelines (up to 500% of the federal poverty limit), and/or requests help with SDOH resources or navigation Participant Exclusion Criteria: Patient is ineligible if he/she is: * Diagnosed with Stage IV disease * Presence of untreated psychiatric disturbance (i.e. acute psychiatric symptoms which require individual treatment) and/or cognitive impairment disorder (e.g., delirium or dementia) verified by medical record sufficient to preclude completion of the assessment measures, interview or informed consent * Has another family member already enrolled in ICCAN (as determined by patient report) ICCAN-IO Phase 1: Refinement, participant is ineligible if he/she per EMR or self-report: * Presence of untreated psychiatric disturbance (e.g., acute psychiatric symptoms which require individual treatment) and/or cognitive impairment disorder (e.g., delirium or dementia) sufficient to preclude completion of the assessment measures, interview or informed consent * Participants or family members who are participating in MSK IHCD studies related to social determinants of health ICCAN-IO Phase 2: Pilot RCT, participant is ineligible if he/she per EMR or self-report: * Presence of untreated psychiatric disturbance (e.g, acute psychiatric symptoms which require individual treatment) and/or cognitive impairment disorder (e.g., delirium or dementia) sufficient to preclude completion of the assessment measures, interview or informed consent * Participants or family members who are participating in MSK IHCD studies related to social determinants of health at the PI's discretion ICCAN-GBM * No recurrences - must be newly diagnosed glioblastoma (per EMR) * Patients undergoing different treatment regimens from the 15 fraction/3 week or 30 fraction/6 week course of radiation (i.e. patients undergoing 10 fractions of palliative radiation due to poor functional status) (per EMR) * Presence of untreated psychiatric disturbance (i.e. acute psychiatric symptoms that require individual treatment) (per EMR or self-report) * Severe cognitive impairment or fluent aphasia as not to understand the assessment measures, interview, or informed consent, without a health care proxy or caregiver that can assist as indicated by clinician or per judgement of study staff. Completion of assessments with the help of caregivers is acceptable. (per EMR or self-report) * Has another family member or household member already enrolled in ICCAN (per self-report) * Already participated in or already completed the ICCAN program (per self-report)
Where it's running
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Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities)
Basking Ridge, New Jersey, United States Recruiting -
Memorial Sloan Kettering Monmouth (Limited Protocol Activities)
Middletown, New Jersey, United States Recruiting -
Memorial Sloan Kettering Bergen (Limited Protocol Activities)
Montvale, New Jersey, United States Recruiting -
Memorial Sloan Kettering Suffolk- Commack (Limited Protocol Activities)
Commack, New York, United States Recruiting -
Memorial Sloan Kettering Westchester (Limited Protocol Activities)
Harrison, New York, United States Recruiting -
City College of New York (Data Collection AND Data Analysis)
New York, New York, United States Recruiting
Show 5 more locations
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Memorial Sloan Kettering at Ralph Lauren Center (Limited Protocol Activities)
New York, New York, United States Recruiting -
Memorial Sloan Kettering Cancer Center
New York, New York, United States Recruiting -
Memorial Sloan Kettering Nassau (Limited Protocol Activities)
Rockville Centre, New York, United States Recruiting -
Lutheran Medical Center
Brooklyn, New York, United States Active not recruiting -
Lincoln Hospital and Mental Health Center
The Bronx, New York, United States Active not recruiting
Study contacts
- Principal investigator: Francesca Gany, MD, MS — Memorial Sloan Kettering Cancer Center
- Study coordinator: Francesca Gany, MD, MS
- Phone: 646-888-8054
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.