Clinical trial Recruiting at 1 site Interventional Ages 55 to 85

Evaluating the effects of walking on pain in older adults

Official title: Exploring the Acute and Dynamic Relationships Between Movement and Pain in Older Adults With Musculoskeletal Pain

Run by Indiana University · NCT06886906 · Data updated 2026-11-12

This study tests if short walks can help reduce pain in older adults who have musculoskeletal pain compared to just sitting.

More Older People trials

Quick facts

Study typeInterventional
Ages55 Years to 85 Years
SexAll
Enrollment40 (estimated)
SponsorIndiana University
Academic / other
Locations1 site (Indianapolis, Indiana)
StatusRecruiting
StartedNovember 13, 2024
Main results expectedJanuary 1, 2027
Study endsJanuary 1, 2027
Registry record updatedOctober 15, 2026
Trial IDNCT06886906 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are community-dwelling older adults who have experienced musculoskeletal pain in the past month.

Probably not a fit

Patients with serious cardiovascular, neurological, or psychiatric conditions, or those unable to walk without assistance may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This research evaluates how brief bouts of intermittent walking affect bodily pain and movement-evoked pain in older adults with musculoskeletal pain. Participants will undergo two sessions where they will experience either uninterrupted sitting or sitting interrupted by light walking, with various assessments including quantitative sensory testing and questionnaires. The study aims to understand the body's adaptation to pain through these different movement conditions.

Why it matters

Potential benefit: If successful, this study could help develop better pain management strategies for older adults suffering from musculoskeletal pain.

How similar studies have gone: Other studies have shown that physical activity can positively influence pain management, suggesting potential success for this approach.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Community-dwelling men and women
* Answer yes to the following question: Have you experienced any musculoskeletal pain (pain affecting joints, bones, ligaments, tendons or muscles) in the past month?

Exclusion Criteria:

* Cardiovascular issues such as uncontrolled blood pressure over 150/99 mmHg, heart failure, or history of acute myocardial infarction;
* Angina in the last month (squeezing, pressure, heaviness, tightness, or pain in chest)
* Serious systemic disease or condition (e.g., severe osteoarthritis, injury) that restricts normal daily activities
* Neurological disease (e.g., Parkinson's Disease, multiple sclerosis, epilepsy)
* Serious psychiatric conditions (schizophrenia, bipolar disorder) or hospitalization within the preceding year for psychiatric illness
* Known peripheral neuropathy
* Chronic opioid use (defined as ≥ 90 days)
* Unable to walk for 6 minutes without assistive devices

Session exclusion criteria:

• Participants will be asked to not participate in vigorous or unaccustomed exercise 48 hours prior to each study session.

Where it's running

  • 250 University Blvd
    Indianapolis, Indiana, United States
    Recruiting

Study contacts

  • Principal investigator: Kelly Marie Naugle — School of Health and Human Sciences, IUPUI
  • Study coordinator: Kelly M Naugle, PhD
  • Email: kmnaugle@iu.edu
  • Phone: +3172740601

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.