Evaluating the effects of oral hydrogen supplements in patients with chronic diseases

To Evaluate the Efficacy of Oral Molecular Hydrogen Supplement in Patients With Chronic Diseases

Phase 2 Interventional HoHo Biotech · NCT06401785

This study is testing whether taking hydrogen supplements can help people with chronic diseases feel better when combined with their regular treatments.

Quick facts

PhasePhase 2
Study typeInterventional
Enrollment60 (estimated)
Ages20 Years to 80 Years
SexAll
SponsorHoHo Biotech Industry-sponsored
Locations2 sites (Taipei and 1 other locations)
Trial IDNCT06401785 on ClinicalTrials.gov

What this trial studies

This study aims to assess the efficacy and safety of oral hydrogen supplements in patients suffering from chronic diseases. Participants will receive hydrogen capsules alongside their conventional treatment for a duration of 24 weeks. The study will involve 60 patients who will be randomly assigned to either an experimental group receiving hydrogen capsules or a control group receiving placebo capsules. Health status, hematologic, and urine analyses will be conducted before and after the intervention to evaluate any changes.

Who should consider this trial

Good fit: Ideal candidates for this study are adults aged 20 to 80 with chronic inflammation or related conditions such as autoimmune diseases, metabolic disorders, or chronic kidney disease.

Not a fit: Patients who are pregnant, expect to become pregnant, or are currently participating in other clinical trials may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide a novel adjunctive treatment option for patients with chronic diseases, potentially improving their recovery and health outcomes.

How similar studies have performed: International clinical trials have shown promise in the efficacy of hydrogen supplements for reducing chronic inflammation, suggesting that this approach may be viable.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age 20 to 80
* Able to compliant with the protocol
* Able to return to the hospital regularly
* Patients with chronic inflammation, including patients with autoimmune diseases, metabolic-related diseases, chronic kidney disease or nephritis, tumor patients, etc.

Exclusion Criteria:

* Pregnancy
* Expected pregnancy
* Attending other clinical trials with 6 months

Where this trial is running

Taipei and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Chronic DiseaseChronic InflammationHydrogen supplementOral hydrogen capsules
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.