Evaluating the EASIX score's impact on sepsis outcomes
Association of Endothelial Activation and Stress Index With Mortality and Poor Prognosis in Sepsis: A Prospective Observational Study
This study is trying to see if the EASIX score can help doctors understand how sepsis affects patients and improve their chances of recovery.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 120 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Sisli Hamidiye Etfal Training and Research Hospital Academic / other |
| Locations | 1 site (Istanbul) |
| Trial ID | NCT06887439 on ClinicalTrials.gov |
What this trial studies
This observational study aims to explore the relationship between the Endothelial Activation and Stress Index (EASIX) score and patient mortality and prognosis in individuals diagnosed with sepsis. Sepsis is a critical condition that leads to organ dysfunction and remains a leading cause of death globally. The study will involve patients over 18 years old who are admitted to intensive care with sepsis, utilizing laboratory parameters to calculate the EASIX score. The findings could enhance early diagnosis and treatment strategies for sepsis.
Who should consider this trial
Good fit: Ideal candidates for this study are adults over 18 years old diagnosed with sepsis during their intensive care admission.
Not a fit: Patients under 18 years old or those with certain pre-existing conditions or who died shortly after diagnosis may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could improve early diagnosis and treatment protocols for sepsis, potentially reducing mortality rates.
How similar studies have performed: While limited retrospective studies have explored the EASIX score in sepsis, this prospective approach is relatively novel and untested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * • Patients diagnosed with sepsis during intensive care admission or admitted to intensive care with a diagnosis of sepsis * All patients over the age of 18 Exclusion Criteria: * • Patients under the age of 18 * Patients with a history of multiple intensive care admissions * Patients who died within 24 hours of diagnosis * Patients diagnosed with CRF or currently treated for ARF * Patients with deficient serum creatinine, LDH and platelet values at the time of diagnosis Patients for whom consent could not be obtained from themselves or their relatives
Where this trial is running
Istanbul
- Sisli etfal research and training hospital — Istanbul, Turkey (Recruiting)
Study contacts
- Study coordinator: Mustafa Altinay
- Email: m_altinay@yahoo.com
- Phone: 05333914422
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.