Evaluating the cost-effectiveness of influenza vaccination in high-risk groups
Acceptability, Cost-Effectiveness, and Capacity of a Facility-Based Seasonal Influenza Vaccination: A Study in Selected Hospitals of Bangladesh
This study is trying to see if giving flu shots during regular health visits is a good idea for high-risk groups in Bangladesh and how it can help improve their health and save money.
Quick facts
| Phase | Phase 4 |
|---|---|
| Study type | Interventional |
| Enrollment | 2567 (estimated) |
| Ages | 6 Months and up |
| Sex | All |
| Sponsor | International Centre for Diarrhoeal Disease Research, Bangladesh Academic / other |
| Locations | 1 site (Rajshahi) |
| Trial ID | NCT05996549 on ClinicalTrials.gov |
What this trial studies
This study aims to assess the acceptability and health beliefs regarding influenza vaccination among high-risk populations in Bangladesh. It will evaluate the cost-effectiveness of providing seasonal influenza vaccinations during routine health facility visits. The study will also explore the necessary infrastructure and capacity required to implement a vaccination program targeting these vulnerable groups. By focusing on high-risk individuals, the research seeks to address the significant health and economic burden posed by influenza in low-income settings.
Who should consider this trial
Good fit: Ideal candidates include children aged six months to eight years, individuals over 60 years, pregnant women, and those with chronic diseases visiting health facilities for routine care.
Not a fit: Patients with severe allergies to vaccine components or a history of severe allergic reactions to previous influenza vaccinations may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved vaccination rates and reduced influenza-related morbidity and mortality among high-risk populations in Bangladesh.
How similar studies have performed: Other studies have shown success in implementing vaccination programs in similar high-risk populations, indicating potential for positive outcomes in this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion criteria: * Participants who will be visiting study hospitals (outpatients and inpatients only. Not emergency departments) for routine care during the study period. * Participants who will be children six months to 8 years or aged more than 60 years or pregnant ( any trimester), or have any chronic disease * Participants /parents/caregivers who will be willing to sign the informed consent form. Exclusion criteria: * Participants with severe, life-threatening allergies to any ingredient in a flu vaccine (other than egg proteins) * Participants having history of a severe allergic reaction (e.g., anaphylaxis) after a previous dose of influenza vaccine or to a vaccine component * Participants having a history of guillain-barre syndrome less than 6 weeks after a previous dose of influenza vaccine * Participants having history of moderate or severe acute illness with or without fever. The vaccine should be given after the acute condition has improved.
Where this trial is running
Rajshahi
- Rajshahi Medical College Hospital — Rajshahi, Bangladesh (Recruiting)
Study contacts
- Study coordinator: Dr. Md. Zakiul Hassan, MSc
- Email: zhassan@icddrb.org
- Phone: +8801753866573
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.