Evaluating the CLEFT-Q questionnaire for patients with cleft lip and palate

Test-Retest Reliability, Responsiveness and Interpretability of CLEFT-Q

Observational Department of Plastic and Reconstructive Surgery · NCT05775679

This study is testing a questionnaire called CLEFT-Q to see how well it works for people with cleft lip and palate in tracking their health and changes after surgery.

Quick facts

Study typeObservational
Enrollment260 (estimated)
Ages8 Years to 29 Years
SexAll
SponsorDepartment of Plastic and Reconstructive Surgery Research network
Locations1 site (Malmö, Skåne County)
Trial IDNCT05775679 on ClinicalTrials.gov

What this trial studies

This observational study aims to assess the reliability and responsiveness of the CLEFT-Q questionnaire in patients with cleft lip and/or palate. It will evaluate whether CLEFT-Q scores remain consistent over time and can detect changes following surgical interventions. Additionally, the study seeks to establish normative data for CLEFT-Q in a control population and identify the Minimal Clinically Important Change across different subpopulations. The research will also explore patient expectations and perceptions regarding surgical outcomes and the impact of CLEFT-Q on clinical decision-making.

Who should consider this trial

Good fit: Ideal candidates include individuals with cleft lip and/or palate who are planning secondary surgeries and can communicate in Swedish.

Not a fit: Patients undergoing multiple surgeries at once may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance the assessment of patient-reported outcomes in cleft lip and palate surgeries, leading to improved patient care.

How similar studies have performed: While the specific application of CLEFT-Q is being evaluated here, similar psychometric assessments have shown promise in other patient populations, indicating potential for success.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Cleft lip and/or palate
* Planned secondary surgery of the nose, lips, jaw or to improve speech
* Can speak and read Swedish

Exclusion Criteria:

* Multiple surgeries at once

Where this trial is running

Malmö, Skåne County

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Cleft Lip and PalateCLEFT-QPsychometricsTest-retest reliabilityInterpretabilityResponsiveness
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.