Evaluating the best timing for periodontal re-evaluation

Clinical Relevance of Different Time of Periodontal Re-evaluation

NA · University of Florence · NCT06086821

This study tests whether checking on gum disease treatment results after 2 weeks or 6 months helps people with periodontitis get better care.

Quick facts

PhaseNA
Study typeInterventional
Enrollment40 (estimated)
Ages18 Years and up
SexAll
SponsorUniversity of Florence (other)
Locations1 site (Florence)
Trial IDNCT06086821 on ClinicalTrials.gov

What this trial studies

This study investigates the optimal timing for re-evaluating periodontal treatment outcomes in patients with periodontitis. Participants will undergo initial treatments aimed at reducing plaque and subgingival biofilm, followed by a re-evaluation at either 2 weeks or 6 months to assess clinical improvements and the need for further therapies. The study aims to determine which timing yields better clinical results, such as pocket depth reduction and overall patient morbidity. By comparing these two intervals, the research seeks to refine treatment protocols for improved patient outcomes.

Who should consider this trial

Good fit: Ideal candidates are adults diagnosed with generalized stage III or IV periodontitis who have specific probing pocket depths and bleeding on probing.

Not a fit: Patients who have received periodontal treatment in the past 12 months or those with certain medical conditions affecting periodontal therapy outcomes may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to more effective periodontal treatment protocols, enhancing patient recovery and reducing the need for additional therapies.

How similar studies have performed: While there have been studies on periodontal treatment timing, this specific approach comparing two distinct re-evaluation intervals is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Adults with a diagnosis of Generalized, stage III or stage IV periodontitis;
* At least 20 teeth present
* At least eight teeth must show probing pocket depths (PPD) of ≥5mm and bleeding on probing (BOP). At least two of these teeth must have a PPD of ≥7 mm and at additional two teeth, the pockets must measure ≥6 mm;

Exclusion Criteria:

* Patients receiving periodontal treatment in the past 12 months;
* Patients receiving antibiotics in the past 3 months;
* Known medical conditions that affects the progression of periodontitis or that affect the outcomes of periodontal therapy;
* Compromised medical conditions requiring prophylactic antibiotic coverage; and ongoing drug therapy that might affect the clinical signs and symptoms of periodontitis.

Where this trial is running

Florence

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Periodontal Diseases, Periodontal Pocket, Periodontal treatment, Non-surgical periodontal treatment

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.