Evaluating the antimicrobial effects of diclofenac sodium in dental treatments

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial aims to assess the effectiveness of diclofenac sodium as an intracanal medicament compared to calcium hydroxide in treating chronic apical periodontitis in permanent molar teeth. Participants will be randomly assigned to receive either diclofenac sodium or calcium hydroxide, and the study will measure bacterial reduction through microbiological assessments before and after treatment. The goal is to determine if diclofenac sodium can serve as a viable alternative to traditional treatments in endodontics.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients with teeth diagnosed with apical periodontitis
* Periapical Index (PAI) ≥ 2
* The teeth are restorable

Exclusion Criteria:

* Teeth with immature roots
* Non restorable teeth
* Medically compromised patients with systemic complication that would alter the treatment.
* Teeth with internal/external root resorption
* Patient with an allergy to diclofenac sodium

Where it's running

• British university in Egypt
  Cairo, Egypt Recruiting

Study contacts

• Study coordinator: Summer M Elsayed, Bachelor
• Email: pg.summer92140015@bue.edu.eg
• Phone: 01000095124

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.