Evaluating staging systems for skin cancer

Comparison of the Prognostic Capacity of Existing Staging Systems for Cutaneous Squamous Cell Carcinoma

Queen Mary University of London · NCT05695222

This study is trying to see how well current staging systems for skin cancer can predict serious outcomes in people with cutaneous squamous cell carcinoma.

Quick facts

Study typeObservational
Enrollment1500 (estimated)
Ages18 Years to 120 Years
SexAll
SponsorQueen Mary University of London (other)
Locations2 sites (London and 1 other locations)
Trial IDNCT05695222 on ClinicalTrials.gov

What this trial studies

This observational study focuses on cutaneous squamous cell carcinoma (CSCC), the second most common form of skin cancer. Researchers will assess existing CSCC cases from two dermatology centers in the UK to evaluate how accurately current staging systems predict the risk of poor outcomes, such as metastasis and mortality. The goal is to validate the predictive power of histological staging classifications and potentially identify improved prediction tools for better patient management.

Who should consider this trial

Good fit: Ideal candidates are individuals over 18 years old diagnosed with cutaneous squamous cell carcinoma.

Not a fit: Patients who decline to allow their data to be used for research purposes will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance the management and treatment outcomes for patients with cutaneous squamous cell carcinoma.

How similar studies have performed: While this study builds on existing knowledge, the approach of validating staging systems in this specific context has not been extensively tested.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Over 18 years old with diagnosis of CSCC

Exclusion Criteria:

* Patients who decline for their data to be used for research purposes

Where this trial is running

London and 1 other locations

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Cutaneous Squamous Cell Carcinoma

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.