Evaluating smartwatch ECG against clinical ECG for childhood cancer survivors

An Evaluation of Concordance of Smartwatch ECG and One Clinical ECG and Comparison of The Two ECGS in Terms of Predictive Risks

Observational St. Jude Children's Research Hospital · NCT05617391

This study is testing if a smartwatch ECG can predict heart problems just as well as a regular ECG for childhood cancer survivors.

Quick facts

Study typeObservational
Enrollment1300 (estimated)
Ages22 Years and up
SexAll
SponsorSt. Jude Children's Research Hospital Academic / other
Locations1 site (Memphis, Tennessee)
Trial IDNCT05617391 on ClinicalTrials.gov

What this trial studies

This observational study aims to compare the effectiveness of a smartwatch ECG with a traditional clinical ECG in predicting cardiomyopathy risk among survivors of childhood cancer. Participants will undergo a 30-second ECG read from their smartwatch during a scheduled clinical appointment. The study also seeks to develop a predictive model based solely on smartwatch ECG data to enhance risk assessment for cardiomyopathy. By analyzing the concordance between the two ECG methods, the study hopes to improve remote monitoring of heart health in this vulnerable population.

Who should consider this trial

Good fit: Ideal candidates are individuals aged 22 or older who are at least five years post-diagnosis of childhood cancer and are participants in the SJLIFE program.

Not a fit: Patients who have previously been diagnosed with cardiomyopathy or are currently on heart medication may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved early detection and monitoring of cardiomyopathy in childhood cancer survivors.

How similar studies have performed: While the use of smartwatch ECGs is a growing field, this specific approach of comparing smartwatch ECGs to clinical ECGs in childhood cancer survivors is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* SJLIFE participant and 22 years of age or older at time of enrollment
* Participant or legal guardian is able and willing to give informed consent
* At least 5 years after childhood cancer diagnosis

Exclusion Criteria:

* Been diagnosed with cardiomyopathy on previous SJLIFE ECG
* Currently on heart medication

Where this trial is running

Memphis, Tennessee

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Childhood CancerCardiomyopathy, Primary
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.