Evaluating sleep disturbances as a marker for PTSD in military personnel

Assessment of Sleep Disturbance as a Biomarker of Disease Activity in a Military Population With Posttraumatic Stress Disorder

Observational Direction Centrale du Service de Santé des Armées · NCT04581850

This study is trying to see if sleep problems can help identify how serious PTSD is in military personnel.

Quick facts

Study typeObservational
Enrollment190 (estimated)
Ages18 Years to 65 Years
SexAll
SponsorDirection Centrale du Service de Santé des Armées Academic / other
Locations6 sites (Clamart and 5 other locations)
Trial IDNCT04581850 on ClinicalTrials.gov

What this trial studies

This observational study aims to assess sleep disturbances in military personnel diagnosed with Post-Traumatic Stress Disorder (PTSD) to understand their role as a biomarker for disease activity. The study will involve sleep recording, cognitive tasks, and questionnaires to gather data on sleep quality and its correlation with PTSD symptoms. By focusing on the military population, which experiences high rates of PTSD and associated sleep issues, the study seeks to uncover the physiological basis of traumatic nightmares and their impact on overall mental health.

Who should consider this trial

Good fit: Ideal candidates include military personnel aged 18 to 65 who have been diagnosed with PTSD.

Not a fit: Patients with pre-existing sleep or psychiatric disorders prior to the traumatic event may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved diagnostic and therapeutic strategies for managing PTSD in military populations.

How similar studies have performed: While the relationship between sleep disturbances and PTSD has been explored, this specific approach focusing on military personnel and the physiological basis of nightmares is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Military or former military
* Age between 18 and 65 years old
* PTSD group : with a PTSD diagnosis
* Control group : without any sleep, psychiatric or neurologic pathology

Exclusion Criteria:

* Diagnosis of progressive psychiatric pathology prior to the traumatic event responsible for PTSD
* Sleep pathology prior to the traumatic event responsible for PTSD
* Neurological pathology or severe head injury within the last 3 years

Where this trial is running

Clamart and 5 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Post-traumatic Stress Disorder
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.