Evaluating sleep and circadian health in ICU survivors
Compromised Sleep and Circadian Health After Critical Illness: From Diagnosis to Prediction (CHRONOCRIT)
This study looks at how being in the ICU affects sleep and daily rhythms in patients, to see if it can help improve their recovery after they leave the hospital.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 271 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Institut de Recerca Biomèdica de Lleida Academic / other |
| Locations | 1 site (Lleida) |
| Trial ID | NCT05995132 on ClinicalTrials.gov |
What this trial studies
This observational study investigates the impact of critical illness on sleep and circadian rhythms in patients who have been admitted to the intensive care unit (ICU). Researchers will assess the expression of microRNA profiles to identify alterations in sleep and circadian health during ICU stays and follow up with patients at 3 and 12 months post-discharge. The study aims to develop machine learning models to predict adverse outcomes related to sleep and circadian health, thereby improving management strategies for critical survivors. By quantifying these alterations, the study seeks to provide healthcare professionals with valuable insights into the long-term effects of ICU care on patients' recovery.
Who should consider this trial
Good fit: Ideal candidates for this study are adults over 18 years old who have been admitted to the ICU for at least 7 days.
Not a fit: Patients who are transferred to another hospital during hospitalization or follow-up, or those receiving palliative care, may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved management of sleep and circadian health in ICU survivors, enhancing their overall recovery and quality of life.
How similar studies have performed: While the specific approach of this study may be novel, previous studies have indicated that addressing sleep and circadian health in ICU survivors is a critical area of research with potential for significant impact.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Being older than 18 years old. * Intensive care unit admission. * Intensive care unit stay ≥7 days. Exclusion Criteria: * Transference to another hospital during hospitalization or follow-up. * Mental or physical disability that could prevent the proposed evaluations. * Palliative care
Where this trial is running
Lleida
- Hospital Universitari Arnau de Vilanova — Lleida, Spain (Recruiting)
Study contacts
- Principal investigator: Adriano Targa Dias Santos, PhD — Institut de Recerca Biomèdica de Lleida
- Study coordinator: Adriano Targa Dias Santos, PhD
- Email: adrianotargads@gmail.com
- Phone: +34 973702491
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.