Evaluating safety and immune response of multiple vaccines in healthy adults aged 18 to 49.

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to assess the safety and immunogenicity of various vaccine formulations targeting influenza and other respiratory viruses in healthy adults aged 18 to 49. Participants will receive a single intramuscular injection of one of the candidate vaccines, which include different doses of trivalent influenza vaccines and a combination vaccine for respiratory syncytial virus, human metapneumovirus, and parainfluenza virus. Throughout the study, participants will document any reactions or adverse events in a diary over a period of approximately six months.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Aged 18 to 49 years on the day of inclusion
* A female participant is eligible to participate if she is not pregnant or breastfeeding and one of the following conditions applies:

  * Is of non-childbearing potential. To be considered of non-childbearing potential, a female must be post-menopausal for at least 1 year, or surgically sterile OR
  * Is of childbearing potential and agrees to use an effective contraceptive method or abstinence from at least 4 weeks prior to study intervention administration until at least 4 weeks after study intervention administration.

Exclusion Criteria:

- Any medical condition or circumstance which, in the opinion of the investigator, might interfere with the evaluation of the study objectives

Note: The above information is not intended to contain all considerations relevant to a patient's potential participation in a clinical trial.

Where it's running

• Paratus Clinical
  Blacktown, New South Wales, Australia Recruiting
• Paratus Clinical
  Herston, Queensland, Australia Recruiting
• University of Sunshine Coast Clinical Trials
  Morayfield, Queensland, Australia Recruiting
• University of Sunshine Coast Clinical Trials
  South Brisbane, Queensland, Australia Recruiting
• Griffith University
  Southport, Queensland, Australia Recruiting
• Emeritus Research
  Camberwell, Victoria, Australia Recruiting

Study contacts

• Study coordinator: Sanofi Trial Transparency Email Recommended (Toll free for US
• Email: contact-us@sanofi.com
• Phone: 800-633-1610 ext Opt. 6

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Influenza Vaccine Immunogenicity in Older Adults with Repeated Vaccination

  This study tests how different flu vaccines perform in adults 65+ who get yearly vaccines to see if age and repeated vaccination affect the immune response.

  Recruiting Phase 4 Korea University Guro Hospital · Seoul · NCT07838298

• Offering the nasal flu vaccine in daycare for young children

  This project will test whether offering the nasal (spray) influenza vaccine at daycare gets more children vaccinated than offering the vaccine only at healthcare clinics.

  Recruiting Turku University Hospital · Turku · NCT07310472

• Evaluating the impact of influenza vaccination and certain medications on COVID-19 outcomes

  This study is trying to see if getting the flu vaccine or taking certain medications helps people in the hospital recover better from COVID-19.

  Recruiting Consorci Sanitari de Terrassa · Terrassa, Barcelona · NCT04367883

• Effects of Exercise Snacks on Muscle Size and Strength in Healthy Young Adults

  This study tests whether many small workouts throughout the week can build muscle size and improve strength in healthy, untrained young adults compared with the usual twice-weekly workouts.

  Recruiting University of British Columbia · Vancouver, British Columbia · NCT07760597

• ORX489 safety and dosing in healthy adults ages 18 to 60

  This will test whether ORX489 tablets are safe, well tolerated, and how they are processed in the body in healthy men and women aged 18 to 60.

  Recruiting Phase 1 Centessa Pharmaceuticals (UK) Limited · Lincoln, Nebraska · NCT07413666

• ReHIIT Prehabilitation in Healthy Adults

  This pilot tests a combined resistance and high‑intensity interval training program to establish baseline physiology in healthy adults before applying findings to cancer patients.

  Recruiting University of Nottingham · Derby, Derbyshire · NCT07313332

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.