Evaluating reversible causes during out-of-hospital cardiac arrest
Relevance of Reversible Causes During OHCA (Rebecca Study)
This study is testing new ways to find treatable causes of cardiac arrest outside the hospital to see if it helps improve CPR performance and patient outcomes.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 100 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Medical University of Vienna Academic / other |
| Locations | 2 sites (Vienna and 1 other locations) |
| Trial ID | NCT05784480 on ClinicalTrials.gov |
What this trial studies
This study focuses on identifying reversible causes of out-of-hospital cardiac arrest (OHCA) using point-of-care diagnostics such as emergency ultrasound, blood gas analysis, and toxicological screening. It aims to implement a structured protocol with an interactive checklist to evaluate these causes and assess their impact on CPR performance and the cognitive load of emergency physicians. A total of 100 patients experiencing OHCA will be included, and the study will analyze various CPR parameters, including hands-off time, return of spontaneous circulation (ROSC), and 30-day mortality rates.
Who should consider this trial
Good fit: Ideal candidates for this study are adults experiencing out-of-hospital cardiac arrest who can undergo point-of-care diagnostics without delaying life-saving treatment.
Not a fit: Patients under 18 years of age, pregnant individuals, or those whose diagnostic procedures would delay critical treatment will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance the management of cardiac arrest by improving the identification of reversible causes, potentially leading to better patient outcomes.
How similar studies have performed: While the approach of using point-of-care diagnostics in emergency settings is gaining traction, this specific study's focus on reversible causes during OHCA is relatively novel and has not been extensively tested in prior studies.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients with prehospital cardiac arrest, where POCUS, blood gas analysis as well as screening for intoxication can integrated in ALS rhythm without delay of life-saving treatment or transportation will be included. Exclusion Criteria: * Patients will be excluded under the age of 18, or if POCUS, blood gas analysis will lead to a delay of live-saving treatment or transportation. Furthermore, pregnant patients will be excluded.
Where this trial is running
Vienna and 1 other locations
- Anesthesiology and Intensive Care Medicine Department - Medical University of Vienna — Vienna, Austria (Not_yet_recruiting)
- Department of Anesthesia, General Intensive Care and Pain Management,Medical University of Vienna — Vienna, Austria (Recruiting)
Study contacts
- Study coordinator: Andreas Schmid, Dr.
- Email: andreas.a.schmid@meduniwien.ac.at
- Phone: 014040024680
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.