Evaluating radiotherapy guided by MRI technology
Prospective Evaluation of Radiotherapy Using Magnetic Resonance Image Guided Treatment
This study is testing a new type of radiotherapy that uses MRI technology to see if it can improve treatment results and reduce side effects for patients.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 200 (estimated) |
| Ages | 5 Years and up |
| Sex | All |
| Sponsor | Institute of Cancer Research, United Kingdom Academic / other |
| Locations | 1 site (London) |
| Trial ID | NCT03727698 on ClinicalTrials.gov |
What this trial studies
This study aims to gather data on patients receiving radiotherapy using a new machine that incorporates magnetic resonance imaging (MR linac) to enhance treatment precision. By collecting information on treatment outcomes and side effects, the study seeks to inform the integration of MR linac into standard clinical practice. The data will be combined with information from other centers using this technology to optimize future radiotherapy protocols.
Who should consider this trial
Good fit: Ideal candidates are children aged 5 to 16 who require radiotherapy suitable for delivery on the MR linac.
Not a fit: Patients with contraindications to MR imaging or those whose radiotherapy needs exceed the capabilities of the MR linac will not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could lead to more effective and personalized cancer treatment with fewer side effects.
How similar studies have performed: Other studies using MR-guided radiotherapy have shown promise, indicating potential for success with this novel approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Radiotherapy treatment suitable to be delivered on the MR Linac. 2. Patient provides written, informed consent and/or authorization. 3. Patients between the ages of 5 and under 16 years old may enter protocol with parental/guardian consent. Exclusion Criteria: 1. Contra-indications to MR imaging. 2. Radiotherapy not suitable for delivery on the MR Linac e.g. those with extended field lengths (exceeding 20 cm).
Where this trial is running
London
- Royal Marsden NHSFT — London, United Kingdom (Recruiting)
Study contacts
- Study coordinator: Robert Huddart
- Email: robert.huddart@icr.ac.uk
- Phone: 44 208 661 3425
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.