Evaluating radiotherapy for head and neck tumors

Radiotherapy Treatments for Neoplasms in the Head and Neck Region

Observational European Institute of Oncology · NCT06335342

This study is testing how well different radiotherapy treatments work for people with tumors in their head and neck and how well patients can tolerate these treatments.

Quick facts

Study typeObservational
Enrollment4050 (estimated)
Ages18 Years and up
SexAll
SponsorEuropean Institute of Oncology Academic / other
Locations1 site (Milan)
Trial IDNCT06335342 on ClinicalTrials.gov

What this trial studies

This observational study aims to evaluate the clinical and dosimetric aspects, tolerance, and effectiveness of radiotherapy treatments for neoplasms located in the head and neck region. It will collect data from patients undergoing radiotherapy for both primary and secondary tumors, focusing on treatment outcomes and patient tolerance. The study will analyze various treatment strategies established through multidisciplinary discussions, taking into account disease characteristics, patient preferences, and functional aspects. The goal is to identify the most effective treatment protocols based on collected data over time.

Who should consider this trial

Good fit: Ideal candidates include patients receiving radiotherapy for primary or secondary neoplasms in the head and neck region.

Not a fit: Patients undergoing radiotherapy for tumors located outside the head and neck region will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved treatment strategies for patients with head and neck neoplasms.

How similar studies have performed: Other studies have shown success in evaluating radiotherapy treatments for similar conditions, indicating that this approach is supported by existing research.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients treated with radiotherapy for curative, palliative, neo-adjuvant, and adjuvant purposes in the head and neck region include those with:

  * Primary bone tumors,
  * Primary soft tissue tumors,
  * Primary tumors of the cardio-circulatory system,
  * Primary tumors of the lymphatic system,
  * Primary tumors of the nervous system and skin,
  * Secondary metastases from various origins localized in that district.
* Signed informed consent

Exclusion Criteria:

• Radiotherapy in districts other than the head and neck region

Where this trial is running

Milan

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Head and Neck Neoplasms
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.