Evaluating quality of life in cancer patients treated with hadrontherapy

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to assess the quality of life (QoL) in patients with solid tumors, specifically head and neck, skull base, and brain cancers, who have undergone hadrontherapy. Two cohorts will be established: one consisting of long-term survivors and another of patients receiving curative intent treatment. Participants will complete standardized questionnaires to evaluate their QoL throughout their oncological journey. The study seeks to fill the gap in existing literature regarding patient-reported outcomes following hadrontherapy.

Why it matters

Who can join: the full rules

Cohort A ("survivors"):

Inclusion Criteria

* Patients with at least a follow up of 5 years with head and neck, skull base and brain tumors and no evidence of progressive disease.
* The patient is able to give consent

Exclusion Criteria:

* Re-irradiation.
* Second tumor.
* Known cases of any psychiatric and neurological diseases leading to disability (eg, manic disorder, schizophrenia etc..), which could impair compilation of questionnaires or affect quality of life.

Cohort B:

Inclusion Criteria:

* Histological and/or radiological diagnosis of head and neck tumors
* Patients candidate for curative intent hadrontherapy
* Patients ≥ 18 years of age
* The patient is able to give consent

Exclusion criteria:

* Re-irradiation.
* Second tumor
* Known cases of any psychiatric and neurological diseases leading to disability (eg, manic disorder, schizophrenia etc..), which could impair compilation of questionnaires or affect quality of life
* Presence of diffused metastasis

Where it's running

• Cnao
  Pavia, Pv, Italy Recruiting

Study contacts

• Principal investigator: Anna Maria Camarda — CNAO National Center of Oncological Hadrontherapy
• Study coordinator: Anna Maria Camarda
• Email: camarda@cnao.it
• Phone: +390382078501

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.