Evaluating quality of life and motor performance in patients with soft tissue sarcomas after surgery

Clinical Evaluation, Motor Performance and Quality of Life in Patients Affected by Soft Tissue Sarcomas, Undergoing Surgical Treatment: Observational Study

Observational Fondazione Policlinico Universitario Campus Bio-Medico · NCT06282237

This study is trying to see how surgery and rehabilitation affect the quality of life and movement in adults with soft tissue sarcomas.

Quick facts

Study typeObservational
Enrollment13 (estimated)
SexAll
SponsorFondazione Policlinico Universitario Campus Bio-Medico Academic / other
Locations1 site (Roma)
Trial IDNCT06282237 on ClinicalTrials.gov

What this trial studies

This observational study aims to assess the quality of life and motor performance in adult patients with localized soft tissue sarcomas who are undergoing surgical treatment and subsequent rehabilitation. The study will identify clinical characteristics and motor impairments following surgery, as well as the impact of perioperative treatments on patients' quality of life. Primary endpoints include improvements in the Toronto Extremity Salvage Score (TESS) from post-surgery to the end of rehabilitation, alongside secondary assessments using various rating scales to evaluate pain and functional outcomes.

Who should consider this trial

Good fit: Ideal candidates are adult patients with primary localized soft tissue sarcoma who are scheduled for curative limb or trunk surgery.

Not a fit: Patients with recurrent tumors, metastatic disease, or those undergoing palliative surgery will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance rehabilitation strategies and improve quality of life for patients recovering from soft tissue sarcoma surgery.

How similar studies have performed: While similar studies have explored quality of life in cancer patients, this specific approach focusing on soft tissue sarcomas and post-operative rehabilitation is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

\- Adult patients affected by primary localized soft tissue sarcoma, candidate to limb/trunk surgery with wide excision or retroperitoneal resection (including resection of the iliopsoas muscle with possible damage to the femoral nerve) with curative intent.

Exclusion Criteria:

* Patients with recurrent tumors;
* patients with metastatic disease;
* patients with palliative surgery;
* patients with amputations.

Where this trial is running

Roma

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Sarcoma
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.