Evaluating quality of life after surgery for advanced ovarian cancer
Assessment of Quality of Life After Low Anterior Resection or Visceral Peritoneal Stripping During cytOreDuctive surgerY for Advanced Ovarian Cancer Requiring Tumor Resection on the Rectosigmoid Colon: a Prospective Cohort Study
Seoul National University Hospital · NCT05431530
This study looks at how surgery for advanced ovarian cancer affects the quality of life and bowel function in patients after their operation.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 108 (estimated) |
| Ages | 18 Years and up |
| Sex | Female |
| Sponsor | Seoul National University Hospital (other) |
| Drugs / interventions | chemotherapy, radiation |
| Locations | 1 site (Seoul) |
| Trial ID | NCT05431530 on ClinicalTrials.gov |
What this trial studies
This observational study assesses the incidence of low anterior resection syndrome and the overall quality of life in patients who have undergone cytoreductive surgery for advanced ovarian cancer. It focuses on individuals who require the removal of tumors from the rectum and sigmoid colon, which can lead to complications affecting bowel function. By monitoring these patients post-surgery, the study aims to gather data on their recovery and the challenges they face related to bowel control and daily living. The findings could provide valuable insights into patient care and management following such surgical interventions.
Who should consider this trial
Good fit: Ideal candidates include adults over 18 with newly diagnosed ovarian cancer or related conditions who are scheduled for cytoreductive surgery.
Not a fit: Patients who have previously undergone low anterior resection or have other significant gastrointestinal issues may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could improve understanding of post-surgical quality of life and lead to better management strategies for patients with advanced ovarian cancer.
How similar studies have performed: While there have been studies on quality of life post-surgery for various cancers, this specific focus on low anterior resection syndrome in ovarian cancer is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Those with newly diagnosed ovarian cancer, fallopian tube cancer and primary peritoneal carcinomatosis who plan to undergo cytoreductive surgery and secondary cytoreductive surgery after neoadjuvant chemotherapy. * Patients with PCDS or rectal and sigmoid coloni tumor invasion suspected on the preoperative image and need resection of the tumor and clinical FIGO stage IIIB or higher * ECOG performance status : 0-2 * Age over 18 Exclusion Criteria: * Patient who underwent low anterior resection in the past * Past history of gastrointestinal malignant tumor except to ovarian cancer * Patient who have colostomy * Patient who underwent radiation therapy to abdominal or pelvic cavity * ECOG performance status over 3 * Patient taking opioid analgesics * Patient who have intellectual disability or dementia
Where this trial is running
Seoul
- Seoul National University Hospital — Seoul, South Korea (RECRUITING)
Study contacts
- Principal investigator: Hee Seung Kim, MD/PhD — Seoul National University Hospital
- Study coordinator: Soo Jin Park, MD
- Email: soojin.mdpark@gmail.com
- Phone: +82-02-2072-2388
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Ovarian Cancer, Low Anterior Resection Syndrome, Quality of Life