Evaluating Proton Therapy for Tumors Previously Treated with Radiation

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial investigates the use of Pencil Beam Scanning Proton Therapy for patients with tumors that have previously been treated with radiation. The study aims to explore different doses and scheduling of proton therapy to effectively target recurrent or new tumors while minimizing damage to surrounding healthy tissues. By utilizing proton therapy, which delivers radiation more precisely than traditional photon therapy, the trial seeks to improve treatment outcomes for patients with various types of cancer, including CNS, head and neck, GI, gynecologic, and prostate cancers.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age 18 years
* Patient provides study specific informed consent prior to study entry.
* Documented history and physical exam within 90 days prior to registration.
* ECOG PS 0, 1, or 2 within 90 days prior to registration

Exclusion Criteria:

* Non malignant systemic disease that would preclude the patient from receiving study treatment or would prevent required follow up.
* Prior invasive non study malignancy unless disease free for ≥ 3 years

  * Non melanoma skin cancer, low risk prostate cancer, well differentiated thyroid cancers, in situ carcinomas of the oral cavity, cervix, and other organs, and tumors that are not thought to impact the life expectancy of the patient are permissible.
* History of active connective tissue disorder (i.e., systemic lupus erythematosus, scleroderma), dermatomyositis, xeroderma pigmentosum

Where it's running

• The New York Proton Center
  New York, New York, United States Recruiting

Study contacts

• Study coordinator: Ryan Holder, BS
• Email: research@nyproton.com
• Phone: 646-968-9055

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.