Evaluating progression and quality of life in patients with age-related macular degeneration
Official title: Evaluation of Clinical Progression, Prognostic Factors, and Quality of Life in Patients with Age-related Macular Degeneration (VERA-nAMD).
Run by University of Udine · NCT06899360 · Data updated 2026-11-12
This study is testing how age-related macular degeneration affects vision and quality of life in people over 50 to see what factors influence the disease's progression.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 50 Years to 120 Years |
| Sex | All |
| Enrollment | 200 (estimated) |
| Sponsor | University of Udine Academic / other |
| Drugs / interventions | ranibizumab |
| Locations | 1 site (Udine, UD) |
| Status | Recruiting |
| Started | October 1, 2024 |
| Main results expected | October 1, 2026 |
| Study ends | October 1, 2029 |
| Registry record updated | March 27, 2025 |
| Trial ID | NCT06899360 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are individuals aged 50 and older with a confirmed diagnosis of age-related macular degeneration in at least one eye.
✕Probably not a fit
Patients with significant ocular or systemic diseases that could affect visual outcomes may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
The VERA-AMD study is a prospective, observational study that aims to evaluate the clinical progression, prognostic factors, and quality of life in patients aged 50 and older with age-related macular degeneration (AMD). By analyzing real-world clinical data from 200 patients, the study seeks to identify key predictors of disease progression and functional outcomes. Primary outcomes include the rate of progression to advanced AMD and changes in visual acuity, while secondary outcomes focus on retinal morphology and quality of life assessments. The study integrates anti-VEGF therapy and AI-based fluid analysis to explore their impact on disease management.
Why it matters
Potential benefit: If successful, this study could lead to improved management strategies for patients with age-related macular degeneration, enhancing their quality of life and visual outcomes.
How similar studies have gone: Other studies have shown success in using observational approaches to understand AMD progression, making this study a valuable addition to existing knowledge.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * age ≥ 50 years. * confirmed diagnosis of AMD in at least one eye. * follow-up scheduled according to standard clinical practice. Exclusion Criteria: * presence of other significant ocular conditions that could affect visual acuity. * systemic conditions that make the patient unsuitable for long-term follow-up.
Where it's running
-
Department of Ophthalmology
Udine, Ud, Italy Recruiting
Study contacts
- Principal investigator: Daniele Veritti — Department of Ophthalmology, University of Udine
- Study coordinator: Daniele Veritti
- Email: daniele.veritti@uniud.it
- Phone: +390432559907
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.