Evaluating physical function assessments in adults with hemophilia
Measurement Properties (Reliability and Validity) of a Set of Assessments Evaluating Physical Function in People with Hemophilia
This study is testing different ways to measure how well adults with hemophilia can move and function to help doctors better understand their needs and treatment options.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 50 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University of Zurich Academic / other |
| Locations | 1 site (Zurich) |
| Trial ID | NCT06565481 on ClinicalTrials.gov |
What this trial studies
This project aims to assess the reliability and validity of various clinical assessments that measure physical function in adults with hemophilia. Given the advancements in hemophilia treatment, individuals still experience mobility restrictions, reduced strength, and pain due to repeated bleeding episodes. The study seeks to validate measurement instruments that can accurately reflect these limitations and their changes over time, ensuring that health professionals can make informed decisions regarding treatment options. By focusing on a relevant population, the research will enhance the clinical assessment of physical function in hemophilia patients.
Who should consider this trial
Good fit: Ideal candidates include adults aged 18 and older diagnosed with Hemophilia A or B who can walk independently for 20 meters.
Not a fit: Patients with severe health conditions or those unable to perform the assessments due to disabilities or language barriers may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved assessment tools that better inform treatment decisions for patients with hemophilia.
How similar studies have performed: While some measurement instruments have been studied in children or other diseases, this specific evaluation in adults with hemophilia is novel and untested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Diagnosed Hemophilia Types A or B * Adult people ≥ 18 years * Patients on prophylactic factor or non-factor replacement treatment, or on demand factor replacement treatment. * Able to walk for 20 meters independently, with or without walking aid * Signed informed consent to participate in the study Exclusion Criteria: * Severe health conditions like severe cardiovascular, pulmonary, neurological or musculoskeletal diseases. * Unable to perform the assessments due to disability or language problems.
Where this trial is running
Zurich
- Ruud Knols — Zurich, Switzerland (Recruiting)
Study contacts
- Principal investigator: Ruud Knols, PhD — University of Zurich
- Study coordinator: Ruud H Knols, PhD
- Email: ruud.knols@usz.ch
- Phone: 0442558809
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.