Evaluating pain management methods for minimally invasive cancer surgery
Evaluating Optimal Perioperative Pain Management: A Prospective Randomized Control Trial of Laparoscopic Transversus Abdominis Plane Block With Local Anesthetic, Laparoscopic Transversus Abdominis Plane Block Alone, and Local Anesthetic Alone in Minimally Invasive Oncologic Surgery
This study is testing which pain management method works best for people undergoing minimally invasive cancer surgery by comparing three different approaches.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 48 (estimated) |
| Ages | 18 Years to 89 Years |
| Sex | All |
| Sponsor | Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute) Academic / other |
| Locations | 1 site (Pittsburgh, Pennsylvania) |
| Trial ID | NCT06731998 on ClinicalTrials.gov |
What this trial studies
This research evaluates the effectiveness of three different pain management regimens during minimally invasive oncologic surgeries. Participants will be randomly assigned to receive either a combination of Laparoscopic Transversus Abdominis Plane Block (LapTAP) with Local Anesthetic, LapTAP alone, or Local Anesthetic alone. The study aims to compare these approaches to determine which provides the best postoperative pain control. Data will be collected from patients' medical records to assess outcomes and refine clinical protocols for pain management in cancer surgery.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 to 89 scheduled for elective minimally invasive oncologic surgeries.
Not a fit: Patients with chronic pain disorders or those on long-term opioid therapy may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved pain management strategies for patients undergoing minimally invasive cancer surgeries.
How similar studies have performed: Preliminary investigations into LapTAP have shown promise, but this study aims to fill a gap in comparative effectiveness research.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Male and female patients age ≥ 18 - 89 2. Patients scheduled for elective (clinically indicated) hepatic, gastric, biliary, pancreatic, gynecologic, colorectal, other GI Minimally invasive oncologic surgery. 3. Patients who have provided informed consent to participate in the study. 4. Patients with an American Society of Anesthesiologists (ASA) physical status classification of I, II, or III. 5. Patients undergoing procedures anticipated to last more than 1 hour but less than 8 hours. 6. Patients able to understand and self-report pain using the designated pain Visual Analog Scale Exclusion Criteria: 1. Patients age less than 18 or ≥ 90 2. Pre-existing hepatic dysfunction, cirrhosis 3. Patients with an ASA classification of IV or higher. 4. Patients with chronic pain disorders or on long-term opioid or analgesic therapy. 5. Patients with known contraindications to the study drugs or procedures (e.g., allergy to LA or contraindications to LapTAP). 6. Patients with cognitive impairments or psychiatric conditions that could interfere with pain assessment or understanding of informed consent. 7. Patients unable to understand the language in which consent and study-related information are provided (The study and the study-related information will be in the English Language).. 8. Patients who have undergone major surgery within the last 6 months. 9. Female patients who are pregnant. 10. Patients currently enrolled in another clinical trial that might interfere with the outcome measures of this study.
Where this trial is running
Pittsburgh, Pennsylvania
- AHN West Penn Hospital — Pittsburgh, Pennsylvania, United States (Recruiting)
Study contacts
- Principal investigator: Casey Allen, MD — Allegheny Health Network
- Study coordinator: Casey Allen, MD
- Email: casey.allen@ahn.org
- Phone: (412) 913-6466
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.