Evaluating oxygen desaturation during low PEEP ventilation in ARDS patients
Safety of Low PEEP Maneuvers During ARDS Management
This study looks at how often patients with moderate to severe ARDS experience low oxygen levels while on a breathing machine using low PEEP settings, to see if this approach is safe and effective.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 50 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Centre Hospitalier Universitaire, Amiens Academic / other |
| Locations | 1 site (Amiens) |
| Trial ID | NCT05922969 on ClinicalTrials.gov |
What this trial studies
This observational study focuses on patients with moderate to severe Acute Respiratory Distress Syndrome (ARDS) who are undergoing mechanical ventilation with low levels of Positive End Expiratory Pressure (PEEP). The study aims to assess the prevalence of oxygen desaturation during ventilatory maneuvers at low PEEP settings, as well as to identify potential risk factors associated with this phenomenon. By closely monitoring these patients, the research seeks to provide insights into the safety and effectiveness of low PEEP strategies in ARDS management.
Who should consider this trial
Good fit: Ideal candidates for this study are adults over 18 years old diagnosed with moderate or severe ARDS who are on mechanical ventilation using low PEEP maneuvers.
Not a fit: Patients who refuse to participate or do not meet the criteria for ARDS and mechanical ventilation will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance the understanding of safe ventilation practices for ARDS patients, potentially improving patient outcomes.
How similar studies have performed: While the specific approach of evaluating oxygen desaturation during low PEEP maneuvers is novel, related studies on PEEP settings in ARDS have shown varying degrees of success.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * age : \> 18 yo * inclusion criteria: ARDS, Mechanical ventilation, low PEEP maneuvers Exclusion Criteria: * refusal to participate
Where this trial is running
Amiens
- CHU Amiens — Amiens, France (Recruiting)
Study contacts
- Study coordinator: Yoann Zerbib, MD
- Email: Zerbib.yoann@chu-amiens.fr
- Phone: 03 22 08 77 23
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.