Clinical trial Recruiting at 31 sites Observational Ages 18 to 90

Evaluating outcomes of esophageal cancer surgery

Official title: National Oesophageal and Gastric Carcinomas Data Base Construction: the FREGAT (French EsoGastric Tumours) Data Base

Run by University Hospital, Lille · NCT02526095 · Data updated 2026-11-12

This study looks at how well surgery works for people with esophageal or stomach cancer, including those who had treatment before, by collecting information from their experiences.

Quick facts

Study typeObservational
Ages18 Years to 90 Years
SexAll
Enrollment15000 (estimated)
SponsorUniversity Hospital, Lille
Academic / other
Locations31 sites (Amiens and 30 other locations)
StatusRecruiting
StartedJune 2014
Main results expectedMay 2027
Study endsMay 2027
Registry record updatedMay 14, 2026
Trial IDNCT02526095 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include adults aged 18 and older with a diagnosis of esophageal, gastric, or gastroesophageal junction cancer who have not received prior treatment.

Probably not a fit

Patients under 18 years old, those unable to consent, or individuals who do not speak French may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study focuses on assessing the outcomes of patients with esophageal cancer, gastric cancer, or gastroesophageal junction tumors following surgical intervention. It includes patients who have not received prior treatment or those who have undergone neoadjuvant therapy. The study collects data retrospectively to analyze the effectiveness of surgical procedures in this patient population. Participants will provide informed consent for blood sampling and complete various questionnaires to aid in data collection.

Why it matters

Potential benefit: If successful, this study could provide valuable insights into the effectiveness of surgical treatments for esophageal cancer, potentially improving patient outcomes.

How similar studies have gone: Other studies evaluating surgical outcomes in esophageal cancer have shown promising results, indicating that this approach is supported by existing research.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria: Patient with

* esophageal cancer, gastric or gastroesophageal junction diagnosed biopsy , regardless of the subtype of cancer, tumor stage or treatment envisaged.
* Naive treatment for this cancer,
* Naive treatment for this cancer , failing that received neoadjuvant treatment ,
* Male or female ≥ 18 years.
* social protection scheme .
* sign a free and informed consent for blood sampling , the different questionnaires and the collection of patient information.

Exclusion Criteria:

Male or female aged ( e) under 18 years.

* Private person of liberty or under supervision (including guardianship ) .
* People who do not speak French.
* Major Nobody unable to consent .
* Patient FREGAT already included in the base.
* Patient Refusal .

Where it's running

  • Chu Amiens Picardie
    Amiens, France
    Recruiting
  • Chru Besancon
    Besançon, France
    Recruiting
  • Hu Paris Site Avicenne Aphp
    Bobigny, France
    Recruiting
  • Chu de Caen Normandie
    Caen, France
    Recruiting
  • Crlcc Francois Baclesse
    Caen, France
    Recruiting
  • Hopital Estaing - Chu63 - Clermont Ferrand
    Clermont-Ferrand, France
    Recruiting
Show 25 more locations
  • Hu Paris Nord Site Louis Mourier Aphp
    Colombes, France
    Recruiting
  • Hopital Le Bocage Chru Dijon
    Dijon, France
    Recruiting
  • Chu de Grenoble Alpes
    Grenoble, France
    Recruiting
  • Hop Claude Huriez Chu Lille
    Lille, France
    Recruiting
  • Clcc Oscar Lambret Lille
    Lille, France
    Recruiting
  • C H U Dupuytren Limoges
    Limoges, France
    Recruiting
  • Hospices Civils de Lyon (Pierre Bénite,Edouard Herriot, La Croix Rousse)
    Lyon, France
    Recruiting
  • Aphm Hopital Nord
    Marseille, France
    Recruiting
  • Hopital St Eloi Chu Montpellier
    Montpellier, France
    Recruiting
  • Icm - Montpellier
    Montpellier, France
    Recruiting
  • Chu de Nantes :Site Hôtel-Dieu- Hme
    Nantes, France
    Recruiting
  • Chu Nimes
    Nîmes, France
    Recruiting
  • Hu Est Parisien Site St Antoine Aphp
    Paris, France
    Recruiting
  • Hu Paris Centre Site Cochin Aphp
    Paris, France
    Recruiting
  • Hu Paris Sud Site Kremlin Bicetre Aphp
    Paris, France
    Recruiting
  • Hu Saint Louis Site Saint Louis Aphp
    Paris, France
    Recruiting
  • Hopital Haut-Leveque - Chu - Pessac
    Pessac, France
    Recruiting
  • Hopital Robert Debre Chu Reims
    Reims, France
    Recruiting
  • Chru Rennes Site Pontchaillou
    Rennes, France
    Recruiting
  • Hopital Charles Nicolle Chu Rouen
    Rouen, France
    Recruiting
  • Hus/Hop Hautepierre
    Strasbourg, France
    Recruiting
  • Hopital Purpan Chu
    Toulouse, France
    Recruiting
  • Chu de Tours
    Tours, France
    Recruiting
  • Institut de Cancerologie de Lorraine
    Vandœuvre-lès-Nancy, France
    Recruiting
  • Institut Gustave Roussy
    Villejuif, France
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.