Evaluating outcomes of esophageal cancer surgery
Official title: National Oesophageal and Gastric Carcinomas Data Base Construction: the FREGAT (French EsoGastric Tumours) Data Base
Run by University Hospital, Lille · NCT02526095 · Data updated 2026-11-12
This study looks at how well surgery works for people with esophageal or stomach cancer, including those who had treatment before, by collecting information from their experiences.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 90 Years |
| Sex | All |
| Enrollment | 15000 (estimated) |
| Sponsor | University Hospital, Lille Academic / other |
| Locations | 31 sites (Amiens and 30 other locations) |
| Status | Recruiting |
| Started | June 2014 |
| Main results expected | May 2027 |
| Study ends | May 2027 |
| Registry record updated | May 14, 2026 |
| Trial ID | NCT02526095 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include adults aged 18 and older with a diagnosis of esophageal, gastric, or gastroesophageal junction cancer who have not received prior treatment.
✕Probably not a fit
Patients under 18 years old, those unable to consent, or individuals who do not speak French may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study focuses on assessing the outcomes of patients with esophageal cancer, gastric cancer, or gastroesophageal junction tumors following surgical intervention. It includes patients who have not received prior treatment or those who have undergone neoadjuvant therapy. The study collects data retrospectively to analyze the effectiveness of surgical procedures in this patient population. Participants will provide informed consent for blood sampling and complete various questionnaires to aid in data collection.
Why it matters
Potential benefit: If successful, this study could provide valuable insights into the effectiveness of surgical treatments for esophageal cancer, potentially improving patient outcomes.
How similar studies have gone: Other studies evaluating surgical outcomes in esophageal cancer have shown promising results, indicating that this approach is supported by existing research.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: Patient with * esophageal cancer, gastric or gastroesophageal junction diagnosed biopsy , regardless of the subtype of cancer, tumor stage or treatment envisaged. * Naive treatment for this cancer, * Naive treatment for this cancer , failing that received neoadjuvant treatment , * Male or female ≥ 18 years. * social protection scheme . * sign a free and informed consent for blood sampling , the different questionnaires and the collection of patient information. Exclusion Criteria: Male or female aged ( e) under 18 years. * Private person of liberty or under supervision (including guardianship ) . * People who do not speak French. * Major Nobody unable to consent . * Patient FREGAT already included in the base. * Patient Refusal .
Where it's running
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Chu Amiens Picardie
Amiens, France Recruiting -
Chru Besancon
Besançon, France Recruiting -
Hu Paris Site Avicenne Aphp
Bobigny, France Recruiting -
Chu de Caen Normandie
Caen, France Recruiting -
Crlcc Francois Baclesse
Caen, France Recruiting -
Hopital Estaing - Chu63 - Clermont Ferrand
Clermont-Ferrand, France Recruiting
Show 25 more locations
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Hu Paris Nord Site Louis Mourier Aphp
Colombes, France Recruiting -
Hopital Le Bocage Chru Dijon
Dijon, France Recruiting -
Chu de Grenoble Alpes
Grenoble, France Recruiting -
Hop Claude Huriez Chu Lille
Lille, France Recruiting -
Clcc Oscar Lambret Lille
Lille, France Recruiting -
C H U Dupuytren Limoges
Limoges, France Recruiting -
Hospices Civils de Lyon (Pierre Bénite,Edouard Herriot, La Croix Rousse)
Lyon, France Recruiting -
Aphm Hopital Nord
Marseille, France Recruiting -
Hopital St Eloi Chu Montpellier
Montpellier, France Recruiting -
Icm - Montpellier
Montpellier, France Recruiting -
Chu de Nantes :Site Hôtel-Dieu- Hme
Nantes, France Recruiting -
Chu Nimes
Nîmes, France Recruiting -
Hu Est Parisien Site St Antoine Aphp
Paris, France Recruiting -
Hu Paris Centre Site Cochin Aphp
Paris, France Recruiting -
Hu Paris Sud Site Kremlin Bicetre Aphp
Paris, France Recruiting -
Hu Saint Louis Site Saint Louis Aphp
Paris, France Recruiting -
Hopital Haut-Leveque - Chu - Pessac
Pessac, France Recruiting -
Hopital Robert Debre Chu Reims
Reims, France Recruiting -
Chru Rennes Site Pontchaillou
Rennes, France Recruiting -
Hopital Charles Nicolle Chu Rouen
Rouen, France Recruiting -
Hus/Hop Hautepierre
Strasbourg, France Recruiting -
Hopital Purpan Chu
Toulouse, France Recruiting -
Chu de Tours
Tours, France Recruiting -
Institut de Cancerologie de Lorraine
Vandœuvre-lès-Nancy, France Recruiting -
Institut Gustave Roussy
Villejuif, France Recruiting
Study contacts
- Study coordinator: Guillaume Piessen, MD, PhD
- Email: guillaume.piessen@chru-lille.fr
- Phone: +3320444407
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Understanding patient preferences for screening tests for Barrett's esophagus and esophageal cancer
This study is trying to understand what patients prefer when it comes to screening tests for Barrett's esophagus and esophageal cancer to help improve current practices.
-
Assessing esophageal function in patients with persistent GERD symptoms despite medication
This study is testing a new way to check how well the esophagus works in people who still have GERD symptoms even after taking medication, to help find better treatments for them.
-
Quality sleep improvement with evening topical therapy for nocturnal GERD
This trial tests a medical device given before bed to see if it reduces nighttime GERD symptoms and improves sleep and quality of life in adults with nocturnal reflux.
-
Investigating the impact of diet on gastroesophageal reflux disease symptoms
This study is testing how sticking to certain diets for a long time can affect symptoms in people with gastroesophageal reflux disease (GERD).
-
Antireflux stitch during one-anastomosis gastric bypass
This study will test whether adding an antireflux stitch during one-anastomosis gastric bypass reduces postoperative reflux and vomiting for patients having that surgery.
-
PF-08098488 in adults with advanced solid tumors
This study tests PF-08098488 in adults whose cancer has progressed or returned after prior treatment.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.