Evaluating outcomes of Deep Brain Stimulation for movement disorders
Official title: Deep Brain Stimulation (DBS) Retrospective Outcomes Study
Run by Boston Scientific Corporation · NCT03664609 · Data updated 2026-11-12
This study looks at how well Deep Brain Stimulation works for people with Parkinson's Disease, Essential Tremor, and Dystonia by reviewing past patient records.
Quick facts
| Study type | Observational |
|---|---|
| Sex | All |
| Enrollment | 5000 (estimated) |
| Sponsor | Boston Scientific Corporation Industry-sponsored |
| Locations | 20 sites (Phoenix, Arizona and 19 other locations) |
| Status | Recruiting |
| Started | March 12, 2019 |
| Main results expected | December 2028 |
| Study ends | December 2028 |
| Registry record updated | October 7, 2026 |
| Trial ID | NCT03664609 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are individuals who have been previously treated with or are eligible for implantation of a Deep Brain Stimulation system.
✕Probably not a fit
Patients who have not undergone Deep Brain Stimulation or are not candidates for the procedure may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to analyze the real-world clinical outcomes of Deep Brain Stimulation (DBS) in patients with Parkinson's Disease, Essential Tremor, and Dystonia through a retrospective review of de-identified patient records. By examining previously treated patients, the study seeks to gather insights into the effectiveness and safety of DBS in managing these conditions. The methodology involves collecting and analyzing data from multiple medical centers to ensure a comprehensive understanding of patient experiences and outcomes.
Why it matters
Potential benefit: If successful, this study could provide valuable insights into the effectiveness of Deep Brain Stimulation, potentially leading to improved treatment strategies for patients with movement disorders.
How similar studies have gone: Other studies have shown promising outcomes with Deep Brain Stimulation for similar conditions, indicating that this approach has been previously validated.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Must be previously treated with or eligible for implantation with a deep brain stimulation system Exclusion Criteria: * No Exclusion Criteria
Where it's running
-
St. Joseph's Hospital & Medical Center
Phoenix, Arizona, United States Recruiting -
Riverside University Health System
Moreno Valley, California, United States Recruiting -
University of California, San Francisco
San Francisco, California, United States Recruiting -
University of Miami Hospital
Miami, Florida, United States Recruiting -
University of South Florida
Tampa, Florida, United States Recruiting -
Wake Forest University School of Medicine
Winston-Salem, North Carolina, United States Recruiting
Show 14 more locations
-
Allegheny General Hospital
Pittsburgh, Pennsylvania, United States Recruiting -
AZ St. Lucas
Ghent, Belgium Recruiting -
AZ Delta
Roeselare, Belgium Recruiting -
Hopital Fondation Adolphe de Rothschild
Paris, France Recruiting -
Uniklinik Köln
Cologne, Germany Recruiting -
Universitaetsklinikum Dusseldorf
Düsseldorf, Germany Recruiting -
Universitaetsklinikum Schleswig-Holstein
Lübeck, Germany Recruiting -
Universitaetsklinikum Wuerzburg
Würzburg, Germany Recruiting -
Fondazione Istituto Neurologico Casimiro Mondino
Pavia, Italy Recruiting -
Hospital Virgen Del Rocio
Seville, Spain Recruiting -
St. Luke's Regional Medical Center
Boise, Idaho, United States Completed -
Albany Medical Center
Albany, New York, United States Completed -
Swedish Neuroscience Institute
Seattle, Washington, United States Completed -
Uniklinikum Jena
Jena, Germany Completed
Study contacts
- Study coordinator: Cleo Mertz
- Email: BSNClinicalTrials@bsci.com
- Phone: 855-213-9890
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Outcomes of radiofrequency ablation for movement disorders
This study looks at how well a specific treatment called radiofrequency ablation works for people with movement disorders like Parkinson's disease and essential tremor.
-
Validation of a deep learning platform for diagnosing isolated dystonia
This study is testing a new deep learning tool to see if it can help doctors diagnose isolated dystonia more accurately and quickly.
-
Understanding brain activity related to speech in neurological diseases
This study is trying to see how brain activity affects speaking in people with neurological disorders like Parkinson's disease and dystonia who are about to have deep brain stimulation surgery.
-
Long-term evaluation of Abbott deep brain stimulation systems for movement disorders
This study is testing how safe and effective Abbott deep brain stimulation systems are for people with movement disorders like Parkinson's disease over a five-year period.
-
Collecting clinical outcomes for deep brain stimulation in movement disorders
This study is tracking the experiences of people with movement disorders like Parkinson's disease who are getting deep brain stimulation to see how well it works and what risks it might have over time.
-
Investigating the relationship between genetic mutations and brain changes in dystonia
This study is trying to see how genetic changes linked to dystonia affect the brain in people with the condition compared to healthy individuals.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.