Evaluating online therapy for adults with OCD
Effect of Stepped Care in Internet-Based Cognitive Behavioral Therapy for Adults With Obsessive-Compulsive Disorder：A Three-Arm Randomized Controlled Trial
This study is testing whether a new online therapy for OCD works better and is more cost-effective than traditional group therapy and usual medical treatment for adults in China.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 114 (estimated) |
| Ages | 18 Years to 50 Years |
| Sex | All |
| Sponsor | Shanghai Mental Health Center Academic / other |
| Locations | 1 site (Shanghai, Shanghai) |
| Trial ID | NCT05528224 on ClinicalTrials.gov |
What this trial studies
This clinical trial aims to assess the efficacy and cost-effectiveness of stepped-care Internet-based cognitive behavioral therapy (SC-ICBT) compared to Cognitive Behavioral Group Therapy (CBGT) and conventional medical treatment (treatment as usual, TAU) for adults with obsessive-compulsive disorder (OCD) in China. Participants will receive one of the three treatments over a period of six weeks, with their progress monitored through individualized assessments. The study will also include a pilot phase to validate the feasibility of SC-ICBT in this population.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 to 50 who meet the diagnostic criteria for OCD and have stable medication for at least 8 weeks.
Not a fit: Patients with severe OCD symptoms, other mental disorders, or high suicide risk may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide a more effective and cost-efficient treatment option for patients with OCD.
How similar studies have performed: Other studies have shown promise in using Internet-based cognitive behavioral therapy for OCD, suggesting potential success for this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Age between 18 and 50 years 2. Satisfied with the diagnostic criteria for OCD in DSM-5. 3. 16≤YBOCS score ≤31 4. Taking medication stably for 8 weeks 5. Education level ⩾6 years 6. Has sufficient audiovisual skills to complete the necessary examinations for the study. 7. Right-handed (this criterion is for fMRI subjects only) 8. Subjects and their guardians understood the study and signed informed consent. Exclusion Criteria: 1. Satisfied with the diagnostic criteria for a mental disorder in DSM-V other than OCD. 2. Obsessive-compulsive symptoms were too severe to participate in the experiment. 3. High risk of suicide. 4. Severe central system or physical disease 5. Pregnant women or women that getting ready for being pregnant and lactating. 6. Other treatments being performed. 7. Uncooperative or unable to complete treatment 8. With metal implants in the body, such as pacemakers, intracranial silver clips, metal dentures, arterial stents, arterial clips, joint metal fixation, or other metal implants, etc. (this criterion is for fMRI subjects only)
Where this trial is running
Shanghai, Shanghai
- Shanghai Mental Health Center — Shanghai, Shanghai, China (Recruiting)
Study contacts
- Study coordinator: Yiwen Wu
- Email: wuyiwenhsd@163.com
- Phone: +86 135 8590 0231
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.