Evaluating neurologic function after emergency intubation
Official title: Post Intubation Neurologic Outcomes in Critically Ill Adults
Run by King Abdulaziz University · NCT05412823 · Data updated 2026-11-12
This study is trying to see how emergency intubation affects brain function in critically ill patients, especially looking at how low oxygen levels during the procedure might impact their recovery.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 1000 (estimated) |
| Sponsor | King Abdulaziz University Academic / other |
| Locations | 1 site (Jeddah) |
| Status | Recruiting |
| Started | July 22, 2022 |
| Main results expected | June 1, 2027 |
| Study ends | August 1, 2027 |
| Registry record updated | August 16, 2022 |
| Trial ID | NCT05412823 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are critically ill patients over 17 years old with good baseline neurologic function who require emergency intubation.
✕Probably not a fit
Patients who are pediatric, pregnant, or have poor baseline neurologic function or primary intracranial pathology may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to assess the neurologic outcomes of critically ill, non-trauma patients who undergo emergency intubation, particularly focusing on the impact of oxygen desaturation during the procedure. It will analyze the frequency and severity of hypoxia experienced during intubation and its correlation with subsequent neurologic function. By understanding these relationships, the study seeks to inform clinical practices that could mitigate hypoxic events during emergency airway management.
Why it matters
Potential benefit: If successful, this study could lead to improved protocols for emergency intubation, potentially reducing the risk of neurologic complications in critically ill patients.
How similar studies have gone: While the specific approach of this study may be novel, previous literature has established the risks associated with hypoxia in critically ill patients, suggesting a need for further investigation.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Good baseline neurologic function (Modified Rankin Scale: 1-3) * Emergency departments * Critical care units * In-patient floors * Patients undergoing emergent intubations as determined by the treating physician * Age\> 17 years old * Good baseline modified rankin scale (mRs 1-3) Exclusion Criteria: * Pediatric patients (17 years of age of less) * Pregnant patients * Intubations occurring in the operating room * Prisoners * Trauma * Status epilepticus * Primary intracranial pathology * Cardiopulmonary arrest * Poor baseline neurologic function (Modified Rankin Scale: 4-5) * Pre-Hospital Intubation
Where it's running
-
King Abdulaziz University Hospital
Jeddah, Saudi Arabia Recruiting
Study contacts
- Study coordinator: Abdullah Bakhsh
- Email: aarbakhsh@kau.edu.sa
- Phone: +966 555080287
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Evaluating the effects of propofol and ketamine on heart stability during intubation
This study tests how the anesthetics propofol and ketamine affect heart stability in critically ill patients during intubation to see which one is safer.
-
Comparing two methods for securing intubation tubes
This study is testing whether a new device for securing breathing tubes works better than the usual method to help prevent complications for patients in intensive care.
-
Comparing video and direct laryngoscopy for intubation by anesthesiology residents
This study tests whether using video laryngoscopy helps first-year anesthesiology residents do intubations more successfully and safely compared to the traditional direct method.
-
Using a Smart Checklist to Improve Pediatric Intubation Safety in ICUs
This study is testing a new digital checklist to see if it can make tracheal intubations safer for children in intensive care units.
-
Using ultrasound to confirm correct intubation in patients
This study tests if using ultrasound can help doctors make sure they are placing breathing tubes in the right spot during surgery to avoid complications.
-
InfasurfAero™ for treating respiratory distress in preterm newborns
This study is testing a new device that delivers a treatment for breathing problems in preterm newborns to see if it helps them breathe better without needing a breathing tube.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.