Evaluating neurologic function after emergency intubation
Post Intubation Neurologic Outcomes in Critically Ill Adults
King Abdulaziz University · NCT05412823
This study is trying to see how emergency intubation affects brain function in critically ill patients, especially looking at how low oxygen levels during the procedure might impact their recovery.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 1000 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | King Abdulaziz University (other) |
| Locations | 1 site (Jeddah) |
| Trial ID | NCT05412823 on ClinicalTrials.gov |
What this trial studies
This observational study aims to assess the neurologic outcomes of critically ill, non-trauma patients who undergo emergency intubation, particularly focusing on the impact of oxygen desaturation during the procedure. It will analyze the frequency and severity of hypoxia experienced during intubation and its correlation with subsequent neurologic function. By understanding these relationships, the study seeks to inform clinical practices that could mitigate hypoxic events during emergency airway management.
Who should consider this trial
Good fit: Ideal candidates for this study are critically ill patients over 17 years old with good baseline neurologic function who require emergency intubation.
Not a fit: Patients who are pediatric, pregnant, or have poor baseline neurologic function or primary intracranial pathology may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved protocols for emergency intubation, potentially reducing the risk of neurologic complications in critically ill patients.
How similar studies have performed: While the specific approach of this study may be novel, previous literature has established the risks associated with hypoxia in critically ill patients, suggesting a need for further investigation.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Good baseline neurologic function (Modified Rankin Scale: 1-3) * Emergency departments * Critical care units * In-patient floors * Patients undergoing emergent intubations as determined by the treating physician * Age\> 17 years old * Good baseline modified rankin scale (mRs 1-3) Exclusion Criteria: * Pediatric patients (17 years of age of less) * Pregnant patients * Intubations occurring in the operating room * Prisoners * Trauma * Status epilepticus * Primary intracranial pathology * Cardiopulmonary arrest * Poor baseline neurologic function (Modified Rankin Scale: 4-5) * Pre-Hospital Intubation
Where this trial is running
Jeddah
- King Abdulaziz University Hospital — Jeddah, Saudi Arabia (RECRUITING)
Study contacts
- Study coordinator: Abdullah Bakhsh
- Email: aarbakhsh@kau.edu.sa
- Phone: +966 555080287
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Intubation Complication, Emergency Intubation, Hypoxia, Neurologic Function