Clinical trial Recruiting at 1 site Observational Ages 18 and up

Evaluating neurologic function after emergency intubation

Official title: Post Intubation Neurologic Outcomes in Critically Ill Adults

Run by King Abdulaziz University · NCT05412823 · Data updated 2026-11-12

This study is trying to see how emergency intubation affects brain function in critically ill patients, especially looking at how low oxygen levels during the procedure might impact their recovery.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment1000 (estimated)
SponsorKing Abdulaziz University
Academic / other
Locations1 site (Jeddah)
StatusRecruiting
StartedJuly 22, 2022
Main results expectedJune 1, 2027
Study endsAugust 1, 2027
Registry record updatedAugust 16, 2022
Trial IDNCT05412823 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are critically ill patients over 17 years old with good baseline neurologic function who require emergency intubation.

Probably not a fit

Patients who are pediatric, pregnant, or have poor baseline neurologic function or primary intracranial pathology may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to assess the neurologic outcomes of critically ill, non-trauma patients who undergo emergency intubation, particularly focusing on the impact of oxygen desaturation during the procedure. It will analyze the frequency and severity of hypoxia experienced during intubation and its correlation with subsequent neurologic function. By understanding these relationships, the study seeks to inform clinical practices that could mitigate hypoxic events during emergency airway management.

Why it matters

Potential benefit: If successful, this study could lead to improved protocols for emergency intubation, potentially reducing the risk of neurologic complications in critically ill patients.

How similar studies have gone: While the specific approach of this study may be novel, previous literature has established the risks associated with hypoxia in critically ill patients, suggesting a need for further investigation.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Good baseline neurologic function (Modified Rankin Scale: 1-3)
* Emergency departments
* Critical care units
* In-patient floors
* Patients undergoing emergent intubations as determined by the treating physician
* Age\> 17 years old
* Good baseline modified rankin scale (mRs 1-3)

Exclusion Criteria:

* Pediatric patients (17 years of age of less)
* Pregnant patients
* Intubations occurring in the operating room
* Prisoners
* Trauma
* Status epilepticus
* Primary intracranial pathology
* Cardiopulmonary arrest
* Poor baseline neurologic function (Modified Rankin Scale: 4-5)
* Pre-Hospital Intubation

Where it's running

  • King Abdulaziz University Hospital
    Jeddah, Saudi Arabia
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.