Evaluating muscle loss in liver cancer patients using blood tests and imaging

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to assess sarcopenia, or muscle loss, in patients diagnosed with hepatocellular carcinoma (HCC) by comparing serum levels of myokines and imaging methods. Myokines are substances in the blood that can influence muscle mass, and their levels may provide insights into the severity of sarcopenia. The study will utilize dynamometry measurements and calculate the Skeletal Muscle Index (SMI) from CT scans to evaluate muscle mass. By improving the assessment of sarcopenia, the study seeks to enhance patient management and outcomes in those with HCC.

Why it matters

Who can join: the full rules

Inclusion criteria:

* New diagnosis of HCC made by radiology and/or histopathology according to EASL criteria, regardless of the degree of hepatic fibrosis (METAVIR F0-F4)
* Availability of a pre-therapeutic three-phase contrast-enhanced abdominal-pelvic CT scan.

Non-inclusion criteria:

* Presence of an active cancer other than HCC
* Uncontrolled HIV infection.

Where it's running

• Damien JOLLY
  Reims, France Recruiting

Study contacts

• Study coordinator: Elia GIGANTE
• Email: egigante@chu-reims.fr
• Phone: 03 26 78 33 43

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Assessing muscle loss and liver health in patients with advanced liver disease

  This study is testing how muscle loss affects liver health in people with advanced liver disease by looking at their body composition and overall well-being over two years.

  Recruiting at 3 sites Linkoeping University · Eksjö and 2 other locations · NCT05502198

• Sarcopenia in Patients After Cardiac Surgery

  This observational study tests how common sarcopenia is after cardiac surgery and whether current care helps improve muscle mass and function.

  Recruiting Universitaire Ziekenhuizen KU Leuven · Leuven · NCT07908472

• Bone marrow mesenchymal stem cell injection for sarcopenia

  This study tests whether CG-BM1, a stem cell injection, can be safely given to adults with sarcopenia to see if it helps improve muscle health.

  Recruiting Phase 1/2 GuangZhou Cellgenes Biotechnology Co., Ltd. · Guangzhou · NCT07865676

• GLP-1 receptor agonist use and muscle health in adults with obesity without diabetes

  This study tests whether GLP-1 receptor agonists affect muscle mass and strength in adults with obesity who don’t have diabetes.

  Recruiting Istanbul Saglik Bilimleri University · Istanbul, Kucukcekmece · NCT07858864

• Sarcopenia and Epidural Steroid Injections in Lumbar Spinal Stenosis

  We’re testing how sarcopenia relates to pain, function, and quality of life after a routine interlaminar epidural steroid injection in people with lumbar spinal stenosis.

  Recruiting Marmara University · Istanbul, Istanbul · NCT07855419

• InstaSure Non-Invasive Finger-Press Test for HCC

  This study tests a non-invasive finger-skin test to help identify hepatocellular carcinoma in adults.

  Recruiting Beijing Municipal Administration of Hospitals · Beijing, Beijing Municipality · NCT07848750

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.