Evaluating MRI T1 Relaxation Time in Rectal Cancer
MRI T1 Relaxation Times in Evaluating Neoadjuvant Treatment of Rectal Cancer
This study is testing if MRI can help doctors see how well treatment is working for people with locally advanced rectal cancer by looking at changes in T1 relaxation time.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 108 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Vejle Hospital Academic / other |
| Locations | 1 site (Vejle, Jylland) |
| Trial ID | NCT05876026 on ClinicalTrials.gov |
What this trial studies
This observational study aims to investigate the T1 relaxation time properties in patients with locally advanced rectal cancer. It focuses on determining the diagnostic performance of MRI T1 relaxation time in identifying fibrosis as a complete response to neoadjuvant treatment. Participants will undergo standard neoadjuvant treatment and follow the regular examination protocol for rectal cancer. The study seeks to enhance understanding of MRI's role in assessing treatment response.
Who should consider this trial
Good fit: Ideal candidates are adults over 18 years old diagnosed with locally advanced rectal cancer.
Not a fit: Patients with contraindications for MRI or those who have undergone previous radiochemotherapy may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could improve the accuracy of diagnosing treatment responses in rectal cancer patients.
How similar studies have performed: While similar studies have explored MRI applications in cancer diagnostics, the specific focus on T1 relaxation time in rectal cancer is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * rectal cancer, age \>18 years Exclusion Criteria: * contraindications for MRI (pacemaker, claustrophobia, implanted medical injectors and nerve stimulators), * previous radiochemotherapy or another disease which investigator judges inappropriate for the persons continued participation.
Where this trial is running
Vejle, Jylland
- Vejle Hospital — Vejle, Jylland, Denmark (Recruiting)
Study contacts
- Study coordinator: Mathias Byriel
- Email: mathias.rosenfeldt.byriel@rsyd.dk
- Phone: 004525658865
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.