Evaluating MRI for liver metastases in colorectal cancer patients
Single-center Ambispective Observational Study on the Role of Magnetic Resonance Imaging (MRI) in the Evaluation of Patient Affected by Hepatic Metastases of Carcinoma of the
This study is testing if MRI can help doctors better manage and plan treatment for colorectal cancer patients whose cancer has spread to the liver.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 100 (estimated) |
| Ages | 18 Years to 85 Years |
| Sex | All |
| Sponsor | Fondazione Policlinico Universitario Agostino Gemelli IRCCS Academic / other |
| Locations | 1 site (Roma) |
| Trial ID | NCT05950503 on ClinicalTrials.gov |
What this trial studies
This observational study aims to assess the effectiveness of Magnetic Resonance Imaging (MRI) in managing patients with metastatic colorectal cancer (mCRC) that has spread to the liver. The study will involve patients who have been diagnosed with colorectal cancer and have measurable liver lesions. By utilizing MRI, the researchers hope to improve the evaluation and treatment planning for these patients. The study will be conducted at a single center, focusing on the role of MRI in clinical decision-making.
Who should consider this trial
Good fit: Ideal candidates for this study are adults over 18 years old with a histological diagnosis of colorectal cancer and measurable liver metastases.
Not a fit: Patients under 18 years old or those unable to undergo MRI due to contraindications will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance the diagnostic accuracy and treatment strategies for patients with liver metastases from colorectal cancer.
How similar studies have performed: While the use of MRI in cancer evaluation is established, this specific approach focusing on liver metastases from colorectal cancer is less common and may provide novel insights.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age \> 18 years; * Histological diagnosis of colorectal cancer; * Presence of liver metastases in the staging exams (chest-abdomen CT with contrast medium or PET-CT with 18-FDG); * At least one measurable liver lesion according to RECIST 1.1 criteria; * Adequate organ and marrow function. Exclusion Criteria: * Age \< 18 years; * Inability to undergo MRI; * Major contraindications to liver surgery; * No written informed consent.
Where this trial is running
Roma
- Policlinico Agostino Gemelli — Roma, Italy (Recruiting)
Study contacts
- Principal investigator: Lisa Salvatore, MD, PhD — Fondazione Policlinico Universitario Agostino Gemelli IRCCS
- Study coordinator: Lisa Salvatore, MD, PhD
- Email: lisa.salvatore@policlinicogemelli.it
- Phone: 0630156318
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.