Evaluating microvascular reactivity in heart transplant patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to assess the evolution of systemic microvascular reactivity in adult heart transplant patients before and two years after transplantation. Using non-invasive techniques such as laser speckle contrast imaging and acetylcholine iontophoresis, the study will evaluate skin microcirculation and correlate findings with clinical variables, hemodynamic, and echocardiographic data. The goal is to identify prognostic factors related to graft vascular disease, which is a leading cause of long-term mortality in heart transplant patients.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* capability to understand the objectives of the research and to fulfill the Term of Consent

Exclusion Criteria:

* Pregnancy, acute infection diagnosis, use of circulatory assistance devices

Where it's running

• Eduardo Tibiriçá
  Rio de Janeiro, Brazil Recruiting

Study contacts

• Study coordinator: Eduardo Tibirica Tibirica, MD, PhD
• Email: etibi@uol.com.br
• Phone: +55-21-99914-6075

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Nationwide Swedish program testing donor-derived cell-free DNA to monitor rejection after heart transplant

  This project tests whether a blood test measuring donor-derived cell-free DNA can help monitor rejection in adults who have had a heart transplant.

  Recruiting Karolinska Institutet · Stockholm · NCT07531784

• Metabolic deterioration after heart transplant determines outcomes

  We'll test whether worsening cardiac and systemic metabolism after a heart transplant predicts heart function and long-term survival in adult transplant recipients.

  Recruiting Heinrich-Heine University, Duesseldorf · Düsseldorf, North Rhine-Westphalia · NCT07372820

• Mapping fat-cell sizes around the coronary arteries to trace inflammation

  This project will test whether differences in fat-cell size next to the coronary arteries can show how inflammation spreads in people having a heart transplant for advanced heart failure.

  Recruiting Institute for Clinical and Experimental Medicine · Prague · NCT07360925

• Multimodal analysis of heart biopsy samples

  This project will take one extra small heart biopsy during a clinically needed procedure to test whether detailed molecular and immune analyses can find disease-specific signatures in adults with cardiomyopathies, myocarditis, cardiac amyloidosis, or after heart transplant.

  Recruiting University Hospital, Essen · Essen, North Rhine-Westphalia · NCT07359690

• Long-term health of children born to mothers who had a solid organ transplant

  This project will look for long-term heart, kidney, and immune system problems in people aged 16 and older who were born to mothers who had a kidney, liver, pancreas, heart, or lung transplant.

  Recruiting University Medical Center Groningen · Groningen, Provincie Groningen · NCT07291258

• Cardiac rehabilitation cohort at Medicine Campus Davos to explore recovery

  This project will follow adults coming to Hochgebirgsklinik Davos for cardiac rehabilitation to see how their heart health and recovery progress over time.

  Recruiting Hochgebirgsklinik Davos · Davos, Kanton Graubünden · NCT07096973

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.