Evaluating methods to improve outcomes for premature babies through placental transfusion techniques

Evaluation of Placental Transfusion Techniques in of Prematurity Related Complications and Hematological Profile

Not applicable Interventional Alexandria University · NCT06812507

This study is testing different ways to give blood from the placenta to premature babies to see which method helps them stay healthier in their first days of life.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment160 (estimated)
Ages1 Minute to 2 Minutes
SexAll
SponsorAlexandria University Academic / other
Locations1 site (Alexandria)
Trial IDNCT06812507 on ClinicalTrials.gov

What this trial studies

This study aims to assess the effectiveness of different placental transfusion methods, including intact umbilical cord milking, cut umbilical cord milking, and delayed cord clamping, in preventing complications associated with prematurity in neonates. The research will monitor premature infants born at or before 32 weeks of gestation during their initial days of life in a neonatal intensive care unit. By comparing these techniques, the study seeks to determine which method may provide the best outcomes for these vulnerable patients.

Who should consider this trial

Good fit: Ideal candidates for this study are premature neonates born at or before 32 weeks of gestation who will be admitted to a neonatal intensive care unit within their first day of life.

Not a fit: Patients who are born after 32 weeks of gestation or have major congenital anomalies will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved health outcomes and reduced complications for premature infants.

How similar studies have performed: Other studies have shown promising results with similar placental transfusion techniques, indicating potential for success in this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
* Inclusion Criteria:

  1. Premature neonates ≤ 32 weeks gestational age regardless birth weight
  2. patients should be admitted to neonatal intensive care unit in the first day of life of life

Exclusion criteria:

* Exclusion Criteria:

Patient with any of the following will be excluded:

1. Major congenital anomalies (complex cyanotic heart disease, major central nervous system anomalies).
2. Evidence of head trauma causing major intracranial hemorrhage.
3. placental abnormalities like : abruptions, placenta previa or retroplacental hematoma.
4. Cord accident, or avulsion at the time of delivery.
5. Refusal to perform the intervention by the obstetrician

Where this trial is running

Alexandria

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions PrematurePlacental Transfusion
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.