Evaluating manual therapy and exercise for headache pain relief

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the effectiveness of three non-pharmacological treatment methods for patients suffering from various types of primary headaches, including tension-type headaches, trigeminal autonomic headaches, and migraines. Participants will be assigned to one of three intervention groups: therapeutic exercise, myofascial release combined with therapeutic exercise, or Mulligan's manual therapy combined with therapeutic exercise. The study will assess the reduction in headache episodes, pain intensity, and duration over a series of evaluations conducted before treatment, immediately after treatment, and at three and six months post-treatment. The control group will receive standard pharmacological treatment and may later switch to one of the intervention groups if desired.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients suffering from primary headache or cervicogenic headache;
* Age \> 18 years;
* signature of the informed consent.

Exclusion Criteria:

* upper cervical spine instability;
* cervical arterial insufficiency
* cervical spine fractures
* pregnancies
* rheumatoid arthritis
* severe cognitive impairment

Where it's running

• Rehabilitation Department Fondazione Policlinico Universitario Campus Bio-Medico
  Roma, Rm, Italy Recruiting

Study contacts

• Principal investigator: Silvia Sterzi, MD — Fondazione Policlinico Universitario Campus Bio-Medico
• Study coordinator: Silvia Sterzi, MD
• Email: s.sterzi@policlinicocampus.it
• Phone: +390622541624

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• HEADS Registry: Headache, Ear, Auditory, Dizziness, and Sinus</n> Registry

  This registry tests whether collecting online symptom reports from adults in the U.S. with sinus, vestibular, ear, or headache symptoms can help improve diagnosis and treatment.

  Recruiting Association of Migraine Disorders · North Kingstown, Rhode Island · NCT07754266

• Immediate neck manual therapy effects on atlas position and neck muscles

  This trial tests two upper neck manual therapy techniques to see their immediate effect on neck alignment, atlas position, and a neck muscle shape in adults with head and neck pain or headaches.

  Recruiting Florida Gulf Coast University · Fort Myers, Florida · NCT07725198

• Vitamin IV lidocaine before fundal pressure to prevent headache after cesarean using spinal anesthesia

  This trial tests whether a single intravenous dose of lidocaine given before fundal pressure during cesarean delivery reduces the chance or severity of headache.

  Recruiting Phase 3 Tanta University · Tanta, Gharbia Governorate · NCT07661758

• Muscle Position and Dry Needling Efficacy

  This study tests whether the position of the upper trapezius during dry needling changes pain and function for people with chronic neck pain.

  Recruiting at 2 sites University of Alcala · Alcalá de Henares, Madrid and 1 other locations · NCT07629141

• Gentle ear vagus nerve stimulation to reduce headache after aneurysm stent coiling

  This study will try a noninvasive ear vagus nerve stimulation device to see if it reduces postoperative headaches in adults having stent-assisted coiling or flow-diverter treatment for unruptured brain aneurysms.

  Recruiting Beijing Tiantan Hospital · Beijing, Beijing Municipality · NCT07479082

• Surgical masks versus N95 masks for operating room nurses' symptoms from surgical smoke

  This test compares whether surgical masks or N95 masks reduce physical symptoms from surgical smoke in operating room nurses.

  Recruiting Bartın Unıversity · Bartın, Bartın · NCT07404956

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.