Evaluating Lung Ultrasound for Interstitial Lung Disease in ICU Patients
"Correlation Between PaO2/FiO2 and Lung Ultrasound Score in Patients Admitted to an Intensive Care Unit With Interstitial Syndrome: A Prospective Physiological Study"
This study is testing if lung ultrasound can help doctors better understand the severity of interstitial lung disease in ICU patients by comparing it to their oxygen levels.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 86 (estimated) |
| Ages | 17 Years and up |
| Sex | All |
| Sponsor | Cliniques universitaires Saint-Luc- Université Catholique de Louvain Academic / other |
| Drugs / interventions | radiation |
| Locations | 2 sites (Haine-Saint-Paul, Hainaut and 1 other locations) |
| Trial ID | NCT05631756 on ClinicalTrials.gov |
What this trial studies
This interventional study aims to assess the correlation between the PaO2/FiO2 ratio and the Lung Ultrasound Score (LUSS) in patients with interstitial syndrome admitted to the ICU. Participants will undergo arterial blood gas analysis and lung ultrasound at baseline, 24 hours, and 48 hours to evaluate the severity of their condition. The study seeks to validate LUSS as a reliable tool for assessing interstitial lung disease severity, potentially improving patient management in critical care settings.
Who should consider this trial
Good fit: Ideal candidates are ICU patients over 17 years old with interstitial syndrome requiring evaluation of their lung condition.
Not a fit: Patients with chronic interstitial lung disease, severe trauma, or those undergoing ECMO may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance the accuracy of diagnosing and monitoring interstitial lung disease in ICU patients, leading to better treatment outcomes.
How similar studies have performed: Previous studies have shown promising results using lung ultrasound in critical care, suggesting this approach may be effective.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: - consent -\>17 years old Exclusion Criteria: * LUSS \< 2 Non Inclusion Criteria: * Patient with pathologies leading to chronic IS * Chronic Obstructive Pulmonary Disease (COPD) or active asthma * Patients under veino-veinous or veino-arterial " Extracorporeal Membrane Oxygenation " (ECMO) * Severe trauma patients * Less than twenty-four hours post operative patients * LUS not feasible: prone position, pneumonectomy history, severe obesity
Where this trial is running
Haine-Saint-Paul, Hainaut and 1 other locations
- Centres Hospitaliers de Jolimont — Haine-Saint-Paul, Hainaut, Belgium (Recruiting)
- Cliniques universitaires saint luc — Brussel, Belgium (Recruiting)
Study contacts
- Principal investigator: Eleonore Vasseur, MD — Cliniques universitaires Saint-Luc- Université Catholique de Louvain
- Study coordinator: Eleonore Vasseur, MD
- Email: eleonore.vasseur@saintluc.uclouvain.be
- Phone: +3227641602
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.