Evaluating liquid biopsy and imaging for breast cancer diagnosis
PERSPECTIVE MONOCENTRIC STUDY: USE OF LIQUID BIOPSY AND DIAGNOSTIC IMAGING IN THE SEARCH FOR CIRCULATING TUMOR DNA IN PATIENTS WITH BREAST CANCER
University of Campania Luigi Vanvitelli · NCT05623241
This study is testing how well liquid biopsies and imaging can help doctors diagnose breast cancer by looking at both the images and genetic information from patients.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 200 (estimated) |
| Ages | 18 Years and up |
| Sex | Female |
| Sponsor | University of Campania Luigi Vanvitelli (other) |
| Locations | 1 site (Naples) |
| Trial ID | NCT05623241 on ClinicalTrials.gov |
What this trial studies
This observational study aims to assess the diagnostic accuracy of mammography in analyzing breast cancer lesions by extracting features related to their texture and morphology. It involves patients diagnosed with breast cancer or those under follow-up, correlating imaging data with genetic and molecular analysis obtained from liquid biopsies. The study will provide structured reports detailing the findings to enhance diagnostic precision.
Who should consider this trial
Good fit: Ideal candidates include patients with biopsy-proven breast cancer or those who have undergone surgery for breast cancer and are willing to participate in a liquid biopsy.
Not a fit: Patients who are pregnant, breastfeeding, or have been operated on for benign or inflammatory diseases may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could improve the accuracy of breast cancer diagnosis and monitoring through advanced imaging and liquid biopsy techniques.
How similar studies have performed: While the approach of combining liquid biopsy with imaging is gaining traction, the specific methodology of this study is relatively novel and has not been extensively tested in prior studies.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * full information on the study and signature of the informed consent * biopsy-proven breast cancer or previous surgery for breast cancer * willingness of the patient to undergo liquid biopsy Exclusion Criteria: * state of pregnancy or breastfeeding * patients operated on for benign or inflammatory diseases
Where this trial is running
Naples
- University "Luigi Vanvitelli" — Naples, Italy (RECRUITING)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Breast Cancer, Liquid Biopsy