Evaluating knee prosthesis outcomes using inertial sensors

Evaluation of the Clinical Outcomes of the Total Knee Prosthesis With Posterior Stabilization Implanted With the Use of Inertial Sensors

Observational Istituto Ortopedico Rizzoli · NCT06321042

This study is testing if using special sensors during knee replacement surgery helps people aged 50 to 85 feel better and move easier afterward.

Quick facts

Study typeObservational
Enrollment40 (estimated)
Ages50 Years to 85 Years
SexAll
SponsorIstituto Ortopedico Rizzoli Academic / other
Locations1 site (Bologna, Italia)
Trial IDNCT06321042 on ClinicalTrials.gov

What this trial studies

This study evaluates the clinical outcomes of a specific total knee arthroplasty (TKA) model implanted with the assistance of inertial sensors. The approach involves using these sensors to guide bone cuts during surgery, aiming to improve the precision of the procedure. Clinical-functional scores will be calculated through patient questionnaires to assess the effectiveness of the implantation. The study focuses on patients aged 50 to 85 who are candidates for primary cemented total knee replacement due to severe knee pain and disability.

Who should consider this trial

Good fit: Ideal candidates are males and females aged 50 to 85 who require primary total knee replacement due to severe knee pain and disability.

Not a fit: Patients who have previously undergone hip or ankle arthroplasty or those unable to provide informed consent may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved durability and functionality of knee prostheses for patients.

How similar studies have performed: While the use of inertial sensors in surgical procedures is an emerging field, similar studies have shown promise in improving surgical outcomes.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Male and female subjects 50 years of age or older and less than 85 years of age (\>50 and \<85 years) who are candidates for primary cemented total knee replacement based on physical examination and medical history, including diagnosis of severe knee pain and disability due to at least one of the following causes:

   * to. Primary or secondary osteoarthritis
   * b. Collagen disorders and/or avascular necrosis of femoral condyle
   * c. Moderate valgus, varus or flexion deformities (HKA between ± 10°, flexion contracture \<10°) -
2. Patients consent and able to complete scheduled study procedures and follow-up assessments.
3. Patients informed about the nature of the study who signed the "informed consent" approved by the ethics committee.

Exclusion Criteria:

* Simultaneous participation in other studies
* Patients not capable of understanding and wanting and therefore unable to sign the informed consent
* Patients who have already undergone hip or ankle arthroplasty, previous osteotomy, with severe axial deformities or suffering from rheumatoid arthritis, diabetes or neuromuscular diseases.

Where this trial is running

Bologna, Italia

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Prosthesis Durability
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.